Literature DB >> 75256

Crossed immunoelectrofocusing of cerebrospinal fluid immunoglobulins.

A Sidén.   

Abstract

The combination of the high separation capacity of isoelectric focusing and the specificity of immunoelectrophoresis gives a valuable tool for protein studies. This technic can be applied to immunoglobulin examinations by using KOCN-treated antibodies isoelectric at pH 5 and performing the immunoelectrophoretic procedure at this pH. CSF and serum samples of patients exhibiting CSF immunoglobulin abnormalities and blood-CSF barrier damages were examined by this method.

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Year:  1977        PMID： 75256     DOI： 10.1007/BF00312923

Source DB:  PubMed          Journal:  J Neurol        ISSN： 0340-5354            Impact factor:   4.849


  15 in total

1.  Plasma protein profiling: the diagnostic evaluation of disorders in plasma protein composition by a new immunoelectrophoretic method.

Authors:  R Scherer; G Ruhenstroth-Bauer
Journal:  Clin Chim Acta       Date:  1976-02-02       Impact factor: 3.786

2.  Isoelectric focusing of CSF proteins in neurological diseases.

Authors:  K G Kjellin; O Vesterberg
Journal:  J Neurol Sci       Date:  1974-10       Impact factor: 3.181

3.  [Comparative results of agar electrophoresis and electrofocalization examination of gamma globulins of the cerebrospinal fluid].

Authors:  P Delmotte
Journal:  Acta Neurol Belg       Date:  1972 Jul-Aug       Impact factor: 2.396

4.  [Quantitative simultaneous immunoelectrophoresis. A micromethod for the simultaneous determination of all serum proteins, including the immunoglobulins].

Authors:  W Stephan; U Frahm
Journal:  Z Klin Chem Klin Biochem       Date:  1971-05

5.  Carbamylated antibodies used for quantitation of human IgG. A routine method.

Authors:  O J Bjerrum; A Ingild; H Lowenstein; B Weeke
Journal:  Scand J Immunol Suppl       Date:  1973

Review 6.  Recent developments in chemical modification and sequential degradation of proteins.

Authors:  G R Stark
Journal:  Adv Protein Chem       Date:  1970

7.  Isoelectric focusing of human urinary proteins in polyacrylamide gel.

Authors:  L Rotbol
Journal:  Clin Chim Acta       Date:  1970-07       Impact factor: 3.786

8.  Aberrant CSF protein fractions found by electrofocusing in multiple sclerosis. A study of 26 cases with clinically verified or probable multiple sclerosis and 2 cases with optic neuritis.

Authors:  K G Kjellin; A Siden
Journal:  Eur Neurol       Date:  1977       Impact factor: 1.710

9.  Gel isoelectric focusing of cerebrospinal fluid proteins: a potential diagnostic tool.

Authors:  P Delmotte
Journal:  Z Klin Chem Klin Biochem       Date:  1971-07

10.  Isoelectric focusing and electrophoresis of cerebrospinal fluid proteins in muscular dystrophies and spinal muscular atrophies.

Authors:  K G Kjellin; H Stibler
Journal:  J Neurol Sci       Date:  1976-01       Impact factor: 3.181
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  5 in total

1.  Isoelectric focusing and crossed immunoelectrofocusing of CSF immunoglobulins in MS.

Authors:  A Sidén
Journal:  J Neurol       Date:  1979-07-11       Impact factor: 4.849

2.  Isoelectric focusing and quantitative estimation of cerebrospinal fluid and serum IgG in idiopathic polyneuropathy.

Authors:  P Livrea; G B Zimatore; I L Simone; M Trojano; V Lepore; V Ferrara; F A Lupo; D Pedone
Journal:  J Neurol       Date:  1980       Impact factor: 4.849

3.  Abnormal CSF immunoglobulin components detected by isoelectric focusing.

Authors:  A Sidén
Journal:  J Neurol       Date:  1980       Impact factor: 4.849

4.  Intrathecal IgG synthesis in multiple sclerosis: comparison between isoelectric focusing and quantitative estimation of cerebrospinal fluid IgG.

Authors:  P Livrea; M Trojano; I L Simone; G B Zimatore; G Lamontanara; R Leante
Journal:  J Neurol       Date:  1981       Impact factor: 4.849

5.  Analysis of immunoglobulin G in multiple sclerosis brain: quantitative and isoelectric focusing studies.

Authors:  P Glynn; H M Gilbert; J Newcombe; M L Cuzner
Journal:  Clin Exp Immunol       Date:  1982-04       Impact factor: 4.330
  5 in total

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