Literature DB >> 7524536

Specificity and editing by apoptosis of virus-induced cytotoxic T lymphocytes.

L K Selin1, R M Welsh.   

Abstract

Recent studies have defined an immunological network by which the acute cytotoxic T-lymphocyte response to viral infection modulates or is modulated by the antigen load and by crossreactive memory T cells. Down regulation of the acute CTL response can be associated with either antigen-dependent or antigen-independent apoptosis, and the host enters a state of immune deficiency as these T cells become sensitized to apoptotic mechanisms.

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Year:  1994        PMID： 7524536     DOI： 10.1016/0952-7915(94)90140-6

Source DB:  PubMed          Journal:  Curr Opin Immunol        ISSN： 0952-7915            Impact factor:   7.486


  10 in total

1.  Dynamics of cytotoxic T-lymphocyte exhaustion.

Authors:  D Wodarz; P Klenerman; M A Nowak
Journal:  Proc Biol Sci       Date:  1998-02-07       Impact factor: 5.349

2.  Generation of cellular immunity to lymphocytic choriomeningitis virus is independent of CD1d1 expression.

Authors:  P M Spence; V Sriram; L Van Kaer; J A Hobbs; R R Brutkiewicz
Journal:  Immunology       Date:  2001-10       Impact factor: 7.397

3.  T-lymphocyte downregulation after acute viral infection is not dependent on CD95 (Fas) receptor-ligand interactions.

Authors:  B L Lohman; E S Razvi; R M Welsh
Journal:  J Virol       Date:  1996-11       Impact factor: 5.103

4.  Identification of the immunodominant H-2K(k)-restricted cytotoxic T-cell epitope in the Borna disease virus nucleoprotein.

Authors:  K Schamel; P Staeheli; J Hausmann
Journal:  J Virol       Date:  2001-09       Impact factor: 5.103

5.  Reduction of otherwise remarkably stable virus-specific cytotoxic T lymphocyte memory by heterologous viral infections.

Authors:  L K Selin; K Vergilis; R M Welsh; S R Nahill
Journal:  J Exp Med       Date:  1996-06-01       Impact factor: 14.307

6.  Fibroblasts prevent apoptosis of IL-2-deprived T cells without inducing proliferation: a selective effect on Bcl-XL expression.

Authors:  W Gombert; N J Borthwick; D L Wallace; H Hyde; M Bofill; D Pilling; P C Beverley; G Janossy; M Salmon; A N Akbar
Journal:  Immunology       Date:  1996-11       Impact factor: 7.397

7.  High levels of anti-human immunodeficiency virus type 1 (HIV-1) memory cytotoxic T-lymphocyte activity and low viral load are associated with lack of disease in HIV-1-infected long-term nonprogressors.

Authors:  C Rinaldo; X L Huang; Z F Fan; M Ding; L Beltz; A Logar; D Panicali; G Mazzara; J Liebmann; M Cottrill
Journal:  J Virol       Date:  1995-09       Impact factor: 5.103

8.  ENV-specific cytotoxic T lymphocyte responses in HIV seronegative health care workers occupationally exposed to HIV-contaminated body fluids.

Authors:  L A Pinto; J Sullivan; J A Berzofsky; M Clerici; H A Kessler; A L Landay; G M Shearer
Journal:  J Clin Invest       Date:  1995-08       Impact factor: 14.808

9.  Bystander activation of cytotoxic T cells: studies on the mechanism and evaluation of in vivo significance in a transgenic mouse model.

Authors:  S Ehl; J Hombach; P Aichele; H Hengartner; R M Zinkernagel
Journal:  J Exp Med       Date:  1997-04-07       Impact factor: 14.307

10.  T cell receptor repertoire for a viral epitope in humans is diversified by tolerance to a background major histocompatibility complex antigen.

Authors:  S R Burrows; S L Silins; D J Moss; R Khanna; I S Misko; V P Argaet
Journal:  J Exp Med       Date:  1995-12-01       Impact factor: 14.307
  10 in total

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