Literature DB >> 7523672

Radiotherapy for bone pain.

P R Needham1, N P Mithal, P J Hoskin.   

Abstract

Painful bone metastases are a common problem for cancer patients. Although current evidence supports the use of a single fraction of radiotherapy as the treatment of choice, many radiotherapists, for a variety of reasons, continue to use fractionated regimens. Over one six month period 105 patients received external beam irradiation for painful bone metastases at the Royal London Hospital (RLH). Thirty-one per cent of the patients were aged 70 or over. The treatment of 97 of these patients was assessed. They had a total of 280 sites treated over the course of their disease. Fifty-nine per cent of sites treated received a fractionated course of radiotherapy. Site significantly influenced fractionation. Overall response rates of 82% were achieved. Fractionation did not appear to influence this. Ten patients received large field irradiation. Fifteen patients had five or more sites irradiated, of whom only one received hemibody irradiation.

Entities:  

Mesh:

Year:  1994        PMID: 7523672      PMCID: PMC1294760     

Source DB:  PubMed          Journal:  J R Soc Med        ISSN: 0141-0768            Impact factor:   5.344


  18 in total

1.  Reanalysis of the RTOG study of the palliation of symptomatic osseous metastasis.

Authors:  P H Blitzer
Journal:  Cancer       Date:  1985-04-01       Impact factor: 6.860

2.  Low dose single fraction radiotherapy in the treatment of metastatic bone pain: a pilot study.

Authors:  P Price; P J Hoskin; D Easton; D Austin; S Palmer; J R Yarnold
Journal:  Radiother Oncol       Date:  1988-08       Impact factor: 6.280

3.  Randomized prospective clinical study of small, large and twice-a-day fraction radiotherapy for painful bone metastases.

Authors:  T Okawa; M Kita; M Goto; H Nishijima; N Miyaji
Journal:  Radiother Oncol       Date:  1988-10       Impact factor: 6.280

4.  The responsiveness of bone metastases to radiotherapy: the effect of site, histology and radiation dose on pain relief.

Authors:  G Arcangeli; A Micheli; G Arcangeli; D Giannarelli; O La Pasta; A Tollis; A Vitullo; S Ghera; M Benassi
Journal:  Radiother Oncol       Date:  1989-02       Impact factor: 6.280

5.  The palliation of symptomatic osseous metastases: final results of the Study by the Radiation Therapy Oncology Group.

Authors:  D Tong; L Gillick; F R Hendrickson
Journal:  Cancer       Date:  1982-09-01       Impact factor: 6.860

6.  Single dose and fractionated palliative irradiation for osseous metastases.

Authors:  C R Penn
Journal:  Clin Radiol       Date:  1976-07       Impact factor: 2.350

7.  Radiation therapy for osseous metastasis.

Authors:  F R Hendrickson; W M Shehata; A B Kirchner
Journal:  Int J Radiat Oncol Biol Phys       Date:  1976 Jan-Feb       Impact factor: 7.038

8.  Single dose palliative irradiation for bony metastasis.

Authors:  M M Qasim
Journal:  Strahlentherapie       Date:  1977-08

9.  Painful bone metastasis: efficacy of radiotherapy assessed by the patients: a randomized trial comparing 4 Gy X 6 versus 10 Gy X 2.

Authors:  E L Madsen
Journal:  Int J Radiat Oncol Biol Phys       Date:  1983-12       Impact factor: 7.038

10.  Prospective randomised trial of single and multifraction radiotherapy schedules in the treatment of painful bony metastases.

Authors:  P Price; P J Hoskin; D Easton; D Austin; S G Palmer; J R Yarnold
Journal:  Radiother Oncol       Date:  1986-08       Impact factor: 6.280

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  2 in total

Review 1.  Radiotherapeutic approaches to metastatic disease.

Authors:  Edward Chow; Jackson Wu; Andrew Loblaw; Carlos A Perez
Journal:  World J Urol       Date:  2003-08-09       Impact factor: 4.226

2.  Comparison of Single Versus Multifraction Radiotherapy in Palliation of Painful Bone Metastases.

Authors:  Anthialisha Nongkynrih; Anil Kumar Dhull; Vivek Kaushal; Rajeev Atri; Rakesh Dhankhar; Karun Kamboj
Journal:  World J Oncol       Date:  2018-06-26
  2 in total

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