Literature DB >> 7522866

Pore morphology effects on the fibrovascular tissue growth in porous polymer substrates.

M C Wake1, C W Patrick, A G Mikos.   

Abstract

The feasibility of developing biodegradable polymer scaffolds to engineer tissues was investigated by studying the effects of pore size on the dynamics of fibrovascular tissue ingrowth. Tissue advanced into amorphous poly(L-lactic acid) porous substrates faster as the pore diameter increased. Porous cylindrical devices of 13.5 mm diameter, 5 mm thickness, and approximately 500 microns pore size were filled completely by tissue 5 days postimplantation. Although prevascularized devices possessed minimal void volume for cell seeding to regenerate metabolic organs, they hold promise in the regeneration of tubular tissues by relying on the epithelization of prevascularized grafts.

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Year:  1994        PMID： 7522866     DOI： 10.1177/096368979400300411

Source DB:  PubMed          Journal:  Cell Transplant        ISSN： 0963-6897            Impact factor:   4.064


  33 in total

1.  Plasmid delivery in vivo from porous tissue-engineering scaffolds: transgene expression and cellular transfection.

Authors:  Jae-Hyung Jang; Christopher B Rives; Lonnie D Shea
Journal:  Mol Ther       Date:  2005-09       Impact factor: 11.454

2.  Biomimetic mineral-organic composite scaffolds with controlled internal architecture.

Authors:  I Manjubala; Alexander Woesz; Christine Pilz; Monika Rumpler; Nadja Fratzl-Zelman; Paul Roschger; Juergen Stampfl; Peter Fratzl
Journal:  J Mater Sci Mater Med       Date:  2005-12       Impact factor: 3.896

3.  Plasmid releasing multiple channel bridges for transgene expression after spinal cord injury.

Authors:  Laura De Laporte; Yang Yang; Marina L Zelivyanskaya; Brian J Cummings; Aileen J Anderson; Lonnie D Shea
Journal:  Mol Ther       Date:  2008-12-02       Impact factor: 11.454

Review 4.  Stem cell bioprocessing: fundamentals and principles.

Authors:  Mark R Placzek; I-Ming Chung; Hugo M Macedo; Siti Ismail; Teresa Mortera Blanco; Mayasari Lim; Jae Min Cha; Iliana Fauzi; Yunyi Kang; David C L Yeo; Chi Yip Joan Ma; Julia M Polak; Nicki Panoskaltsis; Athanasios Mantalaris
Journal:  J R Soc Interface       Date:  2009-03-06       Impact factor: 4.118

5.  Microarchitecture of three-dimensional scaffolds influences cell migration behavior via junction interactions.

Authors:  Brendan A C Harley; Hyung-Do Kim; Muhammad H Zaman; Ioannis V Yannas; Douglas A Lauffenburger; Lorna J Gibson
Journal:  Biophys J       Date:  2008-07-11       Impact factor: 4.033

Review 6.  Controlling the porosity and microarchitecture of hydrogels for tissue engineering.

Authors:  Nasim Annabi; Jason W Nichol; Xia Zhong; Chengdong Ji; Sandeep Koshy; Ali Khademhosseini; Fariba Dehghani
Journal:  Tissue Eng Part B Rev       Date:  2010-08       Impact factor: 6.389

Review 7.  Tissue engineering of oral mucosa: a shared concept with skin.

Authors:  Beste Kinikoglu; Odile Damour; Vasif Hasirci
Journal:  J Artif Organs       Date:  2014-10-18       Impact factor: 1.731

Review 8.  Heart regeneration with engineered myocardial tissue.

Authors:  Kareen L K Coulombe; Vivek K Bajpai; Stelios T Andreadis; Charles E Murry
Journal:  Annu Rev Biomed Eng       Date:  2014-04-24       Impact factor: 9.590

9.  Potency of double-layered poly L-lactic acid scaffold in tissue engineering of tendon tissue.

Authors:  Atsuyuki Inui; Takeshi Kokubu; Takeshi Makino; Issei Nagura; Narikazu Toyokawa; Ryosuke Sakata; Masaru Kotera; Takashi Nishino; Hiroyuki Fujioka; Masahiro Kurosaka
Journal:  Int Orthop       Date:  2009-12-05       Impact factor: 3.075

10.  Scaffold stiffness influences cell behavior: opportunities for skeletal tissue engineering.

Authors:  Roel G M Breuls; Timothy U Jiya; Theo H Smit
Journal:  Open Orthop J       Date:  2008-05-29
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