Literature DB >> 7522806

Epidemiology of meningococcal disease and a community outbreak in Somerset.

D J Gunnell1, N Pearson, B Ley, A Hill.   

Abstract

We describe the epidemiology of meningococcal disease in Somerset and a community outbreak in one district. Fifty-seven cases of meningococcal disease occurred in residents of Somerset between 1 May 1990 and 30 April 1993 (incidence 4.7/100,000/year), of whom six died. Thirteen of the cases occurred in one local authority area in a six month period from 1 November 1992 to 30 April 1993; an incidence of 26.6/100,000/year. Twenty-seven patients were given benzyl-penicillin before admission to hospital. General practitioners were significantly more likely to give benzylpenicillin to patients with rashes. The proportion that received prophylaxis tended to increase after a press release was issued and general practitioners were advised. The number of cases was too small to demonstrate the protective effect of early administration of benzylpenicillin. In five cases the consultant in communicable disease control was not informed for over 12 hours. Thirty-seven of the 48 index cases for whom information was available received rifampicin prophylaxis before discharge from hospital.

Entities:  

Mesh:

Substances:

Year:  1994        PMID: 7522806

Source DB:  PubMed          Journal:  Commun Dis Rep CDR Rev        ISSN: 1350-9349


  1 in total

Review 1.  Effectiveness of antibiotics given before admission in reducing mortality from meningococcal disease: systematic review.

Authors:  Susan J M Hahné; André Charlett; Bernadette Purcell; Susanne Samuelsson; Ivonne Camaroni; Ingrid Ehrhard; Sigrid Heuberger; Maria Santamaria; James M Stuart
Journal:  BMJ       Date:  2006-06-03
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.