Literature DB >> 7522752

[The reversibility of a blockade of corticofugal pulse trains to the neurons of the caudate nucleus in cats evoked by the neurotoxin MPTP].

N N Oleshko.   

Abstract

In anesthetised cats, the number of the caudate nucleus neurons responding to a cortical stimulation with latency less than 8.0 ms, increased within 10-12 days after the MPTP administration and then gradually recovers by the 45th-54th day after the neurotoxin administration. Dopamine seems to exert a protecting-inhibiting effect on transmission of corticofugal glutamatergic impulses travelling towards the neostriatum neurons.

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Year:  1994        PMID: 7522752

Source DB:  PubMed          Journal:  Fiziol Zh Im I M Sechenova        ISSN: 1027-3646


  1 in total

1.  Morphofunctional studies of the interactions of the glutamatergic, cholinergic, and dopaminergic systems in the neostriatum.

Authors:  N N Oleshko
Journal:  Neurosci Behav Physiol       Date:  1998 Jul-Aug
  1 in total

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