Literature DB >> 7521714

Monitoring drug use in palliative care.

R G Twycross1, S Bergl, S John, K Lewis.   

Abstract

A computerized system for monitoring drug use which makes use of the British National Formulary (BNF) drug categories and a departmental formulary (DF) has been developed. Data entry takes less than one week of secretarial time per annum. Details of drug use in 385 patients three weeks after referral to a National Health Service palliative care unit over five years form the basis of this report. The median number of drugs per patient was five, with a maximum of 11; 97% of the drugs were from the DF. Analgesics were the commonest category of drugs used. The 10 most commonly used drugs included three analgesics (morphine, co-proxamol, flurbiprofen), two laxatives (co-danthrusate, lactulose), dexamethasone, metoclopramide, ranitidine, temazepam and amitriptyline/dothiepin. Seventeen per cent of patients received two preparations from the same second level BNF category (analgesics excluded). The concurrence was questionable in about half of these, and mostly related to the use of laxatives or to hypnotics and anxiolytics. Several unexpected inclusions in the top 10 drugs illustrate the need for quantification rather than pontification about drug use in palliative care. Examination of duplicate prescribing provides a forum for examining ways of simplifying drug regimens.

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Year:  1994        PMID: 7521714     DOI: 10.1177/026921639400800207

Source DB:  PubMed          Journal:  Palliat Med        ISSN: 0269-2163            Impact factor:   4.762


  9 in total

1.  Changes in medication profile among patients with advanced cancer admitted to an acute palliative care unit.

Authors:  David Hui; Zhijun Li; Gary B Chisholm; Neha Didwaniya; Eduardo Bruera
Journal:  Support Care Cancer       Date:  2014-08-16       Impact factor: 3.603

2.  Potential for drug interactions involving cytochrome P450 in patients attending palliative day care centres: a multicentre audit.

Authors:  A Wilcock; J Thomas; J Frisby; M Webster; V Keeley; G Finn; K Fossey; B Wee; J Beale; M S Lennard
Journal:  Br J Clin Pharmacol       Date:  2005-09       Impact factor: 4.335

Review 3.  Prescribing practices, patterns, and potential harms in patients receiving palliative care: A systematic scoping review.

Authors:  Cathal A Cadogan; Melanie Murphy; Miriam Boland; Kathleen Bennett; Sarah McLean; Carmel Hughes
Journal:  Explor Res Clin Soc Pharm       Date:  2021-07-23

4.  [What is the profile of palliative care in Germany. Results of a representative survey].

Authors:  L Radbruch; C Ostgathe; F Elsner; F Nauck; C Bausewein; M Fuchs; G Lindena; K Neuwöhner; D Schulenberg
Journal:  Schmerz       Date:  2004-06       Impact factor: 1.107

5.  Symptom and medication profiles among cancer patients attending a palliative care clinic.

Authors:  Rachel P Riechelmann; Monika K Krzyzanowska; Aoife O'Carroll; Camilla Zimmermann
Journal:  Support Care Cancer       Date:  2007-04-12       Impact factor: 3.603

Review 6.  [Glucocorticoids and androgens for treatment of tiredness and weakness in palliative care patients : a systematic review].

Authors:  A Thiem; R Rolke; L Radbruch
Journal:  Schmerz       Date:  2012-09       Impact factor: 1.107

7.  Corticosteroid prescribing in palliative care settings: a retrospective analysis in New Zealand.

Authors:  Anne Denton; John Shaw
Journal:  BMC Palliat Care       Date:  2014-03-08       Impact factor: 3.234

8.  Corticosteroids in palliative care - perspectives of clinicians involved in prescribing: a qualitative study.

Authors:  Anne Denton; John Shaw
Journal:  BMC Palliat Care       Date:  2014-11-18       Impact factor: 3.234

9.  Identifying, highlighting and reducing polypharmacy in a UK hospice inpatient unit using improvement Science methods.

Authors:  Alison Phippen; Jennie Pickard; Douglas Steinke; Matt Cope; Dai Roberts
Journal:  BMJ Qual Improv Rep       Date:  2017-03-10
  9 in total

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