E F Branigan1, C H Muller. 1. University of Washington School of Medicine, Division of Reproductive Endocrinology and Infertility, Seattle 98105.
Abstract
OBJECTIVE: To identify men with leukocytospermia and prostatitis in an infertility practice and evaluate the effect of various treatments and recurrence rates after treatment. DESIGN: A prospective randomized trial of men with leukocytospermia. SETTING:Academic tertiary infertility clinic. PATIENTS: One hundred two men with leukocytosperimia identified on smear of semen using Bryan-Leishman stain and in expressed prostatic secretion. INTERVENTIONS: Treatment groups were no treatment group; antibiotic treatment alone group; frequent ejaculation alone group; and antibiotic treatment with frequent ejaculation group. MAIN OUTCOME MEASURE: Resolution of leukocytospermia on semen smear. RESULTS:Significant resolution of leukocytospermia occurred in all treatment groups at 1 month compared with no treatment. The resolution was sustained at 2 and 3 months only in those who took antibiotics and frequently ejaculated. CONCLUSIONS: Antibiotic treatment, frequent ejaculation, and antibiotic treatment with frequent ejaculation effectively treat leukocytospermia immediately after the treatment phase. However, only antibiotic treatment coupled with frequent ejaculation is effective 3 months after treatment.
RCT Entities:
OBJECTIVE: To identify men with leukocytospermia and prostatitis in an infertility practice and evaluate the effect of various treatments and recurrence rates after treatment. DESIGN: A prospective randomized trial of men with leukocytospermia. SETTING: Academic tertiary infertility clinic. PATIENTS: One hundred two men with leukocytosperimia identified on smear of semen using Bryan-Leishman stain and in expressed prostatic secretion. INTERVENTIONS: Treatment groups were no treatment group; antibiotic treatment alone group; frequent ejaculation alone group; and antibiotic treatment with frequent ejaculation group. MAIN OUTCOME MEASURE: Resolution of leukocytospermia on semen smear. RESULTS: Significant resolution of leukocytospermia occurred in all treatment groups at 1 month compared with no treatment. The resolution was sustained at 2 and 3 months only in those who took antibiotics and frequently ejaculated. CONCLUSIONS: Antibiotic treatment, frequent ejaculation, and antibiotic treatment with frequent ejaculation effectively treat leukocytospermia immediately after the treatment phase. However, only antibiotic treatment coupled with frequent ejaculation is effective 3 months after treatment.
Authors: Guntram Bezold; Joseph A Politch; Nancy B Kiviat; Jane M Kuypers; Hans Wolff; Deborah J Anderson Journal: Fertil Steril Date: 2007-04-11 Impact factor: 7.329
Authors: Martin Ludwig; Andreas Vidal; Thorsten Diemer; Wolfgang Pabst; Klaus Failing; Wolfgang Weidner Journal: World J Urol Date: 2003-04-11 Impact factor: 4.226