PURPOSE: To assess the outcome of fetuses with isolated mild ventriculomegaly (IMVM). MATERIALS AND METHODS: The clinical course of 44 fetuses with IMVM was investigated. Cognitive and motor development was classified as normal or delayed. RESULTS: Clinical data were available for 37 subjects. Three (8%) neonates died. Of the 34 living children, follow-up was limited (< 9 months) in six and the clinical course beyond the 1st year of life was established in 28. Twenty-two (79%) of the 28 children are developing normally, whereas six (21%) are developmentally delayed. More than 90% of fetuses with ventricular atrial diameter of 10-11 mm are normal. Seventy-five percent of fetuses with IMVM were male. With exclusion of the six children with limited follow-up, 78% of boys older than 1 year are developmentally normal compared with only 50% of girls. CONCLUSION: The majority of living children with prenatally detected IMVM are developmentally normal, especially those with borderline ventriculomegaly. Gender differences in prevalence and outcome deserve further investigation.
PURPOSE: To assess the outcome of fetuses with isolated mild ventriculomegaly (IMVM). MATERIALS AND METHODS: The clinical course of 44 fetuses with IMVM was investigated. Cognitive and motor development was classified as normal or delayed. RESULTS: Clinical data were available for 37 subjects. Three (8%) neonates died. Of the 34 living children, follow-up was limited (< 9 months) in six and the clinical course beyond the 1st year of life was established in 28. Twenty-two (79%) of the 28 children are developing normally, whereas six (21%) are developmentally delayed. More than 90% of fetuses with ventricular atrial diameter of 10-11 mm are normal. Seventy-five percent of fetuses with IMVM were male. With exclusion of the six children with limited follow-up, 78% of boys older than 1 year are developmentally normal compared with only 50% of girls. CONCLUSION: The majority of living children with prenatally detected IMVM are developmentally normal, especially those with borderline ventriculomegaly. Gender differences in prevalence and outcome deserve further investigation.
Authors: João Fernando Kazan-Tannus; Vandana Dialani; Milliam L Kataoka; Gloria Chiang; Henry A Feldman; Jeffrey S Brown; Deborah Levine Journal: AJR Am J Roentgenol Date: 2007-07 Impact factor: 3.959
Authors: Amanda E Lyall; Sandra Woolson; Honor M Wolfe; Barbara Davis Goldman; J Steven Reznick; Robert M Hamer; Weili Lin; Martin Styner; Guido Gerig; John H Gilmore Journal: Early Hum Dev Date: 2012-03-22 Impact factor: 2.079
Authors: Yi Li; Judy A Estroff; Tejas S Mehta; Richard L Robertson; Caroline D Robson; Tina Y Poussaint; Henry A Feldman; Janet Ware; Deborah Levine Journal: AJR Am J Roentgenol Date: 2011-06 Impact factor: 3.959