| Literature DB >> 7519374 |
P Demange1, D Voges, J Benz, S Liemann, P Göttig, R Berendes, A Burger, R Huber.
Abstract
Annexin V is a Ca(2+)-dependent membrane-binding protein that forms voltage-dependent Ca2+ channels in phospholipid bilayers and is the first ion channel to be structurally and functionally characterized. Data outlined here indicate that key amino acid residues act as selectivity filters and voltage sensors, thereby regulating the permeability of the channel pore to ions.Entities:
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Year: 1994 PMID: 7519374 DOI: 10.1016/0968-0004(94)90002-7
Source DB: PubMed Journal: Trends Biochem Sci ISSN: 0968-0004 Impact factor: 13.807