Literature DB >> 7519373

A G protein involved in nucleocytoplasmic transport: the role of Ran.

M S Moore1, G Blobel.   

Abstract

Ran is the only known member of the Ras superfamily of small GTP-binding proteins to be localized primarily inside the nucleus. Recently, Ran was unexpectedly identified as one of the soluble factors required for nuclear import. As this protein has also been implicated in RNA export, nuclear import and export may be more closely related than previously thought, with Ran playing a key role in each.

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Year:  1994        PMID： 7519373     DOI： 10.1016/0968-0004(94)90024-8

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN： 0968-0004            Impact factor:   13.807


  50 in total

1.  In vitro and in vivo evidence that protein and U1 snRNP nuclear import in somatic cells differ in their requirement for GTP-hydrolysis, Ran/TC4 and RCC1.

Authors:  C Marshallsay; A Dickmanns; F R Bischoff; H Ponstingl; E Fanning; R Lührmann
Journal:  Nucleic Acids Res       Date:  1996-05-15       Impact factor: 16.971

2.  A protein required for nuclear-protein import, Mog1p, directly interacts with GTP-Gsp1p, the Saccharomyces cerevisiae ran homologue.

Authors:  M Oki; T Nishimoto
Journal:  Proc Natl Acad Sci U S A       Date:  1998-12-22       Impact factor: 11.205

3.  The nuclear localization sequence of the SV40 T antigen promotes transgene uptake and expression in zebrafish embryo nuclei.

Authors:  P Collas; H Husebye; P Aleström
Journal:  Transgenic Res       Date:  1996-11       Impact factor: 2.788

4.  Mtr10p functions as a nuclear import receptor for the mRNA-binding protein Npl3p.

Authors:  B Senger; G Simos; F R Bischoff; A Podtelejnikov; M Mann; E Hurt
Journal:  EMBO J       Date:  1998-04-15       Impact factor: 11.598

5.  Topogenesis of a nucleolar protein: determination of molecular segments directing nucleolar association.

Authors:  R F Zirwes; A P Kouzmenko; J M Peters; W W Franke; M S Schmidt-Zachmann
Journal:  Mol Biol Cell       Date:  1997-02       Impact factor: 4.138

6.  In vitro reconstitution of a heterotrimeric nucleoporin complex consisting of recombinant Nsp1p, Nup49p, and Nup57p.

Authors:  N L Schlaich; M Häner; A Lustig; U Aebi; E C Hurt
Journal:  Mol Biol Cell       Date:  1997-01       Impact factor: 4.138

7.  OSBP-related protein 4L promotes phospholipase Cβ3 translocation from the nucleus to the plasma membrane in Jurkat T-cells.

Authors:  Guoping Pan; Xiuye Cao; Bo Liu; Chaowen Li; Dan Li; Jie Zheng; Chaofeng Lai; Vesa M Olkkonen; Wenbin Zhong; Daoguang Yan
Journal:  J Biol Chem       Date:  2018-09-20       Impact factor: 5.157

Review 8.  Nucleocytoplasmic transport of macromolecules.

Authors:  A H Corbett; P A Silver
Journal:  Microbiol Mol Biol Rev       Date:  1997-06       Impact factor: 11.056

9.  A role for the divergent actin gene, ACT2, in nuclear pore structure and function.

Authors:  C Yan; N Leibowitz; T Mélèse
Journal:  EMBO J       Date:  1997-06-16       Impact factor: 11.598

10.  Separate domains of the Ran GTPase interact with different factors to regulate nuclear protein import and RNA processing.

Authors:  M Ren; A Villamarin; A Shih; E Coutavas; M S Moore; M LoCurcio; V Clarke; J D Oppenheim; P D'Eustachio; M G Rush
Journal:  Mol Cell Biol       Date:  1995-04       Impact factor: 4.272
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