Literature DB >> 7519265

Application of dual parameter analysis in flow cytometric DNA measurements of paraffin-embedded samples.

K Nylander1, R Stenling, H Gustafsson, G Roos.   

Abstract

In a comparison of flow cytometric DNA measurements on fresh and paraffin-embedded material from primary squamous cell carcinomas of the head and neck region, we discovered that previously undetected aneuploid clones could be detected by dual parameter analysis of cytokeratin and DNA applied to disintegrated cells from paraffin sections. Using this new approach the correlation coefficient between DNA-indices from fresh and paraffin-embedded material increased from 0.423 to 0.904.

Entities:  

Mesh:

Substances:

Year:  1994        PMID: 7519265     DOI: 10.1111/j.1600-0714.1994.tb01111.x

Source DB:  PubMed          Journal:  J Oral Pathol Med        ISSN: 0904-2512            Impact factor:   4.253


  1 in total

1.  Multiparameter DNA content analysis identifies distinct groups in primary breast cancer.

Authors:  J H S Dayal; M J Sales; W E Corver; C A Purdie; L B Jordan; P R Quinlan; L Baker; N T ter Haar; N R Pratt; A M Thompson
Journal:  Br J Cancer       Date:  2013-02-14       Impact factor: 7.640

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.