Literature DB >> 7518810

Interstrain conservation of babesial RAP-1 surface-exposed B-cell epitopes despite rap-1 genomic polymorphism.

C E Suarez1, T F McElwain, I Echaide, S Torioni de Echaide, G H Palmer.   

Abstract

Members of the babesial rhoptry-associated protein 1 (RAP-1) family express surface-exposed B-cell epitopes and are candidate antigens for vaccine development. The relationship between rap-1 genomic polymorphism and surface-exposed B-cell epitope expression was analyzed by comparison of biological clones of Mexico strain Babesia bigemina and Babesia bovis with strains isolated in Argentina. Despite genomic polymorphism between strains, including sequences located within the open reading frame, defined RAP-1 B-cell surface epitopes and RAP-1 molecular size were conserved in both B. bovis and B. bigemina.

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Year:  1994        PMID： 7518810      PMCID： PMC302997          DOI： 10.1128/iai.62.8.3576-3579.1994

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  24 in total

1.  Identification of Babesia bigemina and Babesia bovis merozoite proteins with isolate- and species-common epitopes recognized by antibodies in bovine immune sera.

Authors:  T F McElwain; G H Palmer; W L Goff; T C McGuire
Journal:  Infect Immun       Date:  1988-06       Impact factor: 3.441

2.  In vitro inhibition of multiplication of Babesia bigemina by using monoclonal antibodies.

Authors:  J V Figueroa; G M Buening
Journal:  J Clin Microbiol       Date:  1991-05       Impact factor: 5.948

3.  Identification of Babesia bovis merozoite surface antigens by using immune bovine sera and monoclonal antibodies.

Authors:  W L Goff; W C Davis; G H Palmer; T F McElwain; W C Johnson; J F Bailey; T C McGuire
Journal:  Infect Immun       Date:  1988-09       Impact factor: 3.441

4.  The immune response of cattle to Babesia bovis (syn. B. argentina). Studies on the nature and specificity of protection.

Authors:  D F Mahoney; J D Kerr; B V Goodger; I G Wright
Journal:  Int J Parasitol       Date:  1979-08       Impact factor: 3.981

5.  A recombinant surface protein of Babesia bovis elicits bovine antibodies that react with live merozoites.

Authors:  D W Reduker; D P Jasmer; W L Goff; L E Perryman; W C Davis; T C McGuire
Journal:  Mol Biochem Parasitol       Date:  1989-07       Impact factor: 1.759

6.  Characterization of the gene encoding a 60-kilodalton Babesia bovis merozoite protein with conserved and surface exposed epitopes.

Authors:  C E Suarez; G H Palmer; D P Jasmer; S A Hines; L E Perryman; T F McElwain
Journal:  Mol Biochem Parasitol       Date:  1991-05       Impact factor: 1.759

7.  Cryopreservation of Babesia bovis for in vitro cultivation.

Authors:  D A Palmer; G M Buening; C A Carson
Journal:  Parasitology       Date:  1982-06       Impact factor: 3.234

8.  Immunity in cattle to Babesia bovis after single infections with parasites of various origin.

Authors:  D F Mahoney; I G Wright; B V Goodger
Journal:  Aust Vet J       Date:  1979-01       Impact factor: 1.281

9.  Antibodies define multiple proteins with epitopes exposed on the surface of live Babesia bigemina merozoites.

Authors:  T F McElwain; L E Perryman; W C Davis; T C McGuire
Journal:  J Immunol       Date:  1987-04-01       Impact factor: 5.422

10.  Molecular characterization of Babesia bovis merozoite surface proteins bearing epitopes immunodominant in protected cattle.

Authors:  S A Hines; T F McElwain; G M Buening; G H Palmer
Journal:  Mol Biochem Parasitol       Date:  1989-11       Impact factor: 1.759
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  9 in total

1.  Characterization of allelic variation in the Babesia bovis merozoite surface antigen 1 (MSA-1) locus and identification of a cross-reactive inhibition-sensitive MSA-1 epitope.

Authors:  C E Suarez; M Florin-Christensen; S A Hines; G H Palmer; W C Brown; T F McElwain
Journal:  Infect Immun       Date:  2000-12       Impact factor: 3.441

2.  Babesia bovis merozoite surface antigen 1 and rhoptry-associated protein 1 are expressed in sporozoites, and specific antibodies inhibit sporozoite attachment to erythrocytes.

Authors:  Juan Mosqueda; Terry F McElwain; David Stiller; Guy H Palmer
Journal:  Infect Immun       Date:  2002-03       Impact factor: 3.441

3.  Babesia bovis merozoite surface antigen 2 proteins are expressed on the merozoite and sporozoite surface, and specific antibodies inhibit attachment and invasion of erythrocytes.

Authors:  Juan Mosqueda; Terry F McElwain; Guy H Palmer
Journal:  Infect Immun       Date:  2002-11       Impact factor: 3.441

4.  The Babesia bovis merozoite surface antigen 2 locus contains four tandemly arranged and expressed genes encoding immunologically distinct proteins.

Authors:  Monica Florin-Christensen; Carlos E Suarez; Stephen A Hines; Guy H Palmer; Wendy C Brown; Terry F McElwain
Journal:  Infect Immun       Date:  2002-07       Impact factor: 3.441

5.  Validation of a competitive enzyme-linked immunosorbent assay for detection of antibodies against Babesia bovis.

Authors:  Will L Goff; John B Molloy; Wendell C Johnson; Carlos E Suarez; Ignacio Pino; Abdelkebir Rhalem; Hamid Sahibi; Luigi Ceci; Grazia Carelli; D Scott Adams; Travis C McGuire; Donald P Knowles; Terry F McElwain
Journal:  Clin Vaccine Immunol       Date:  2006-09-06

6.  Babesia bovis rhoptry-associated protein 1 is immunodominant for T helper cells of immune cattle and contains T-cell epitopes conserved among geographically distant B. bovis strains.

Authors:  W C Brown; T F McElwain; B J Ruef; C E Suarez; V Shkap; C G Chitko-McKown; W Tuo; A C Rice-Ficht; G H Palmer
Journal:  Infect Immun       Date:  1996-08       Impact factor: 3.441

7.  Molecular basis for variable expression of merozoite surface antigen gp45 among American isolates of Babesia bigemina.

Authors:  T G Fisher; T F McElwain; G H Palmer
Journal:  Infect Immun       Date:  2001-06       Impact factor: 3.441

8.  Competitive enzyme-linked immunosorbent assay based on a rhoptry-associated protein 1 epitope specifically identifies Babesia bovis-infected cattle.

Authors:  Will L Goff; Terry F McElwain; Carlos E Suarez; Wendell C Johnson; Wendy C Brown; Junzo Norimine; Donald P Knowles
Journal:  Clin Diagn Lab Immunol       Date:  2003-01

9.  Genotypic diversity of merozoite surface antigen 1 of Babesia bovis within an endemic population.

Authors:  Audrey O T Lau; Karla Cereceres; Guy H Palmer; Debbie L Fretwell; Monica J Pedroni; Juan Mosqueda; Terry F McElwain
Journal:  Mol Biochem Parasitol       Date:  2010-04-03       Impact factor: 1.759
  9 in total

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