Literature DB >> 7518069

Dermatome mapping in the rat hindlimb by electrical stimulation of the spinal nerves.

Y Takahashi1, Y Nakajima, T Sakamoto.   

Abstract

In rats treated with Evans blue (i.v.), electrical stimulation of the lumbar spinal nerves produced an extravasation zone in the skin. Stimulation of L1 produced extravasation in the lower abdomen; that of L2, in the cranial region of the hindlimb; that of L3, in the ventral region of the hindlimb and the medial paw; that of L4, in the lateral region of the hindlimb and the middle paw; that of L5, in the caudal region of the hindlimb and the lateral paw; and that of L6, in the caudal region of the hindlimb and the scrotum. Since the substance P antagonist FK224 inhibited the extravasation caused by stimulation of the sciatic nerve, the extravasation zones appeared to be related to antidromic activation of afferent C-fibers. Thus, a dermatome of afferent C-fibers was revealed in rats.

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Year:  1994        PMID： 7518069     DOI： 10.1016/0304-3940(94)90422-7

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN： 0304-3940            Impact factor:   3.046


  16 in total

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4.  Dorsal Root Ganglion Stimulation Alleviates Pain-related Behaviors in Rats with Nerve Injury and Osteoarthritis.

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6.  Brain-derived neurotrophic factor increases in the uninjured dorsal root ganglion neurons in selective spinal nerve ligation model.

Authors:  T Fukuoka; E Kondo; Y Dai; N Hashimoto; K Noguchi
Journal:  J Neurosci       Date:  2001-07-01       Impact factor: 6.167

7.  Annular puncture with tumor necrosis factor-alpha injection enhances painful behavior with disc degeneration in vivo.

Authors:  Alon Lai; Andrew Moon; Devina Purmessur; Branko Skovrlj; Damien M Laudier; Beth A Winkelstein; Samuel K Cho; Andrew C Hecht; James C Iatridis
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8.  Protein kinase D isoforms are expressed in rat and mouse primary sensory neurons and are activated by agonists of protease-activated receptor 2.

Authors:  Silvia Amadesi; Andrew D Grant; Graeme S Cottrell; Natalya Vaksman; Daniel P Poole; Enrique Rozengurt; Nigel W Bunnett
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9.  Interleukin-1β increased the expression of protease-activated receptor 4 mRNA and protein in dorsal root ganglion neurons.

Authors:  Zhaojin Wang; Dan Chen; Rui Zhang; Shuhong An; Zaifeng Zhang; Qingyuan Ma
Journal:  Neurochem Res       Date:  2013-06-18       Impact factor: 3.996

Review 10.  Contribution of the spared primary afferent neurons to the pathomechanisms of neuropathic pain.

Authors:  Tetsuo Fukuoka; Koichi Noguchi
Journal:  Mol Neurobiol       Date:  2002-08       Impact factor: 5.590
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