Literature DB >> 7517396

Cloning and analysis of a locus (mcr) involved in mitomycin C resistance in Streptomyces lavendulae.

P R August1, M C Flickinger, D H Sherman.   

Abstract

Two genes (mcrA and mcrB) from Streptomyces lavendulae that together confer resistance to mitomycin C were identified. This DNA appears to comprise a polycistronic operon with a drug-inducible leaderless mRNA. The deduced amino acid sequence of mcrA shows similarity to sequences of a special class of bacterial, plant, and animal oxygen oxidoreductases.

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Year:  1994        PMID： 7517396      PMCID： PMC205660          DOI： 10.1128/jb.176.14.4448-4454.1994

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  19 in total

1.  In vivo translational start site selection on leaderless mRNA transcribed from the Streptomyces fradiae aph gene.

Authors:  R L Jones; J C Jaskula; G R Janssen
Journal:  J Bacteriol       Date:  1992-07       Impact factor: 3.490

Review 2.  Compilation and analysis of DNA sequences associated with apparent streptomycete promoters.

Authors:  W R Strohl
Journal:  Nucleic Acids Res       Date:  1992-03-11       Impact factor: 16.971

3.  Modulation of mitomycin cross-linking by DNA bending in the Escherichia coli CAP protein-DNA complex.

Authors:  C Cera; D M Crothers
Journal:  Biochemistry       Date:  1989-05-02       Impact factor: 3.162

4.  Isolation and sequence analysis of a complementary DNA encoding rat liver L-gulono-gamma-lactone oxidase, a key enzyme for L-ascorbic acid biosynthesis.

Authors:  T Koshizaka; M Nishikimi; T Ozawa; K Yagi
Journal:  J Biol Chem       Date:  1988-02-05       Impact factor: 5.157

5.  Induction and purification of stereospecific nicotine oxidizing enzymes from Arthrobacter oxidans.

Authors:  K Decker; H Bleeg
Journal:  Biochim Biophys Acta       Date:  1965-08-24

6.  Isolation and structure of a covalent cross-link adduct between mitomycin C and DNA.

Authors:  M Tomasz; R Lipman; D Chowdary; J Pawlak; G L Verdine; K Nakanishi
Journal:  Science       Date:  1987-03-06       Impact factor: 47.728

7.  6-Hydroxy-D-nicotine oxidase of Arthrobacter oxidans. Gene structure of the flavoenzyme and its relationship to 6-hydroxy-L-nicotine oxidase.

Authors:  R Brandsch; A E Hinkkanen; L Mauch; H Nagursky; K Decker
Journal:  Eur J Biochem       Date:  1987-09-01

8.  Reductive activation of mitomycin C.

Authors:  B M Hoey; J Butler; A J Swallow
Journal:  Biochemistry       Date:  1988-04-05       Impact factor: 3.162

9.  Molecular cloning, expression, and induction of berberine bridge enzyme, an enzyme essential to the formation of benzophenanthridine alkaloids in the response of plants to pathogenic attack.

Authors:  H Dittrich; T M Kutchan
Journal:  Proc Natl Acad Sci U S A       Date:  1991-11-15       Impact factor: 11.205

10.  DNA sequence specificity of mitomycin cross-linking.

Authors:  S P Teng; S A Woodson; D M Crothers
Journal:  Biochemistry       Date:  1989-05-02       Impact factor: 3.162
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  20 in total

Review 1.  Avoidance of suicide in antibiotic-producing microbes.

Authors:  Eric Cundliffe; Arnold L Demain
Journal:  J Ind Microbiol Biotechnol       Date:  2010-05-06       Impact factor: 3.346

2.  The Streptomyces peucetius drrC gene encodes a UvrA-like protein involved in daunorubicin resistance and production.

Authors:  N Lomovskaya; S K Hong; S U Kim; L Fonstein; K Furuya; R C Hutchinson
Journal:  J Bacteriol       Date:  1996-06       Impact factor: 3.490

3.  Characterization of a mitomycin-binding drug resistance mechanism from the producing organism, Streptomyces lavendulae.

Authors:  P J Sheldon; D A Johnson; P R August; H W Liu; D H Sherman
Journal:  J Bacteriol       Date:  1997-03       Impact factor: 3.490

4.  A putative FAD-binding domain in a distinct group of oxidases including a protein involved in plant development.

Authors:  A R Mushegian; E V Koonin
Journal:  Protein Sci       Date:  1995-06       Impact factor: 6.725

Review 5.  Arac/XylS family of transcriptional regulators.

Authors:  M T Gallegos; R Schleif; A Bairoch; K Hofmann; J L Ramos
Journal:  Microbiol Mol Biol Rev       Date:  1997-12       Impact factor: 11.056

Review 6.  Mitomycinoid alkaloids: mechanism of action, biosynthesis, total syntheses, and synthetic approaches.

Authors:  Phillip D Bass; Daniel A Gubler; Ted C Judd; Robert M Williams
Journal:  Chem Rev       Date:  2013-05-08       Impact factor: 60.622

7.  Genetic localization and molecular characterization of two key genes (mitAB) required for biosynthesis of the antitumor antibiotic mitomycin C.

Authors:  Y Mao; M Varoglu; D H Sherman
Journal:  J Bacteriol       Date:  1999-04       Impact factor: 3.490

Review 8.  Comparison of Antibiotic Resistance Mechanisms in Antibiotic-Producing and Pathogenic Bacteria.

Authors:  Hiroshi Ogawara
Journal:  Molecules       Date:  2019-09-21       Impact factor: 4.411

9.  Mitomycin resistance in Streptomyces lavendulae includes a novel drug-binding-protein-dependent export system.

Authors:  P J Sheldon; Y Mao; M He; D H Sherman
Journal:  J Bacteriol       Date:  1999-04       Impact factor: 3.490

10.  Intragenic deletion in the gene encoding L-gulonolactone oxidase causes vitamin C deficiency in pigs.

Authors:  Lara Hasan; Peter Vögeli; Peter Stoll; Spela Spilar Kramer; Gerald Stranzinger; Stefan Neuenschwander
Journal:  Mamm Genome       Date:  2004-04       Impact factor: 2.957
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