Literature DB >> 7516297

Transdermal scopolamine for reduction of drooling in developmentally delayed children.

D W Lewis1, C Fontana, L K Mehallick, Y Everett.   

Abstract

Ten developmentally delayed children with excessive drooling were randomized in a double-blind, placebo-controlled study to assess the efficacy and safety of transdermal scopolamine. Over half of the patients had a statistically significant reduction in drooling, and one-third had cessation of drooling, while wearing the scopolamine patch. This short-term study supports earlier reports of the safety and efficacy of transdermal scopolamine for reducing excessive drooling in developmentally disabled children.

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Year:  1994        PMID: 7516297     DOI: 10.1111/j.1469-8749.1994.tb11877.x

Source DB:  PubMed          Journal:  Dev Med Child Neurol        ISSN: 0012-1622            Impact factor:   5.449


  13 in total

1.  A search for the evidence supporting community paediatric practice.

Authors:  M C Rudolf; N Lyth; A Bundle; G Rowland; A Kelly; S Bosson; M Garner; P Guest; M Khan; R Thazin; T Bennett; D Damman; V Cove; V Kaur
Journal:  Arch Dis Child       Date:  1999-03       Impact factor: 3.791

Review 2.  A systematic review for evidence of efficacy of anticholinergic drugs to treat drooling.

Authors:  P H Jongerius; P van Tiel; J van Limbeek; F J M Gabreëls; J J Rotteveel
Journal:  Arch Dis Child       Date:  2003-10       Impact factor: 3.791

Review 3.  Transdermal scopolamine for prevention of motion sickness : clinical pharmacokinetics and therapeutic applications.

Authors:  Zohar Nachum; Avi Shupak; Carlos R Gordon
Journal:  Clin Pharmacokinet       Date:  2006       Impact factor: 6.447

4.  Management of symptoms in amyotrophic lateral sclerosis.

Authors:  Lisa S Thibodeaux; Amparo Gutierrez
Journal:  Curr Treat Options Neurol       Date:  2008-03       Impact factor: 3.598

Review 5.  Amyotrophic lateral sclerosis: update for family physicians.

Authors:  Christen L Shoesmith; Michael J Strong
Journal:  Can Fam Physician       Date:  2006-12       Impact factor: 3.275

6.  Drooling in children.

Authors:  A K Leung; C P Kao
Journal:  Paediatr Child Health       Date:  1999-09       Impact factor: 2.253

7.  Management of drooling in disabled patients with scopolamine patches.

Authors:  Abigail Mato; Jacobo Limeres; Inmaculada Tomás; Maria Muñoz; Concepción Abuín; Javier F Feijoo; Pedro Diz
Journal:  Br J Clin Pharmacol       Date:  2010-06       Impact factor: 4.335

8.  [Amyotrophic lateral sclerosis: management of bulbar symptoms].

Authors:  P Kraft; M Beck; A Grimm; C Wessig; K Reiners; K V Toyka
Journal:  Nervenarzt       Date:  2010-10       Impact factor: 1.214

9.  Respiratory Failure or Impairment in Amyotrophic Lateral Sclerosis.

Authors:  Deborah F. Gelanis
Journal:  Curr Treat Options Neurol       Date:  2001-03       Impact factor: 3.972

10.  Comparative study of hyoscine doses as antisialagogue for patients receiving ketofol sedation undergoing colonoscopy procedures.

Authors:  Atef Kamal Salama; Hassan Mohamed Ali
Journal:  Anesth Essays Res       Date:  2016 Jan-Apr
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