| Literature DB >> 7515688 |
L Abrami1, M Simon, G Rousselet, V Berthonaud, J M Buhler, P Ripoche.
Abstract
A new member of the family of water channel proteins (aquaporin-CHIP) related to the major intrinsic protein (MIP) family is described. The cDNA coding for this amphibian CHIP was cloned from frog (Rana esculenta) urinary bladder, a model for the kidney collecting duct, using a RT-PCR cloning strategy. The encoded protein, designated FA-CHIP (frog aquaporin-CHIP), shows 77.4%, 42.4% and 35.6% identity with the three proteins now referred to as the aquaporins of the MIP family, i.e., human CHIP28, WCH-CD and gamma-TIP, respectively. Xenopus leavis injected with FA-CHIP cRNA exhibited a marked increase of the osmotic water permeability.Entities:
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Year: 1994 PMID： 7515688 DOI： 10.1016/0005-2736(94)90155-4
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002