Literature DB >> 7515415

Hypoxemia and increased fetal hemoglobin synthesis.

H Bard1, J C Fouron, C Gagnon, J Gagnon.   

Abstract

Fetal hemoglobin (HbF) synthesis in children with congenital cyanotic heart disease was compared that in normal children. Children with hypoxemia had higher levels of hemoglobin, total HbF, and HbF synthesis. In these children there was also an inverse correlation between HbF synthesis and oxygen content, as well as between HbF synthesis and hemoglobin concentration. Thus hypoxemia increases HbF synthesis.

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Year:  1994        PMID： 7515415     DOI： 10.1016/s0022-3476(05)83188-9

Source DB:  PubMed          Journal:  J Pediatr        ISSN： 0022-3476            Impact factor:   4.406


  5 in total

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Journal:  Blood       Date:  2010-12-21       Impact factor: 22.113

2.  Fetal hemoglobin silencing in humans.

Authors:  Patricia A Oneal; Nicole M Gantt; Joseph D Schwartz; Natarajan V Bhanu; Y Terry Lee; John W Moroney; Christopher H Reed; Alan N Schechter; Naomi L C Luban; Jeffery L Miller
Journal:  Blood       Date:  2006-05-30       Impact factor: 22.113

3.  Activation of γ-globin expression by hypoxia-inducible factor 1α.

Authors:  Ruopeng Feng; Thiyagaraj Mayuranathan; Peng Huang; Phillip A Doerfler; Yichao Li; Yu Yao; Jingjing Zhang; Lance E Palmer; Kalin Mayberry; Georgios E Christakopoulos; Peng Xu; Chunliang Li; Yong Cheng; Gerd A Blobel; M Celeste Simon; Mitchell J Weiss
Journal:  Nature       Date:  2022-10-12       Impact factor: 69.504

4.  HIF prolyl hydroxylase inhibition results in endogenous erythropoietin induction, erythrocytosis, and modest fetal hemoglobin expression in rhesus macaques.

Authors:  Matthew M Hsieh; N Seth Linde; Aisha Wynter; Mark Metzger; Carol Wong; Ingrid Langsetmo; Al Lin; Reginald Smith; Griffin P Rodgers; Robert E Donahue; Stephen J Klaus; John F Tisdale
Journal:  Blood       Date:  2007-06-08       Impact factor: 22.113

5.  Fetal Hemoglobin is Associated with Peripheral Oxygen Saturation in Sickle Cell Disease in Tanzania.

Authors:  Siana Nkya; Josephine Mgaya; Florence Urio; Abel Makubi; Swee Lay Thein; Stephan Menzel; Sharon E Cox; Charles R Newton; Fenella J Kirkham; Bruno P Mmbando; Julie Makani
Journal:  EBioMedicine       Date:  2017-08-08       Impact factor: 8.143
  5 in total

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