Literature DB >> 7513815

On the scoring of FISH-"painted" chromosome-type exchange aberrations.

J R Savage1, P Simpson.   

Abstract

The effectiveness of FISH painting for easy detection of radiation-induced chromosome aberrations lies, principally, in the fact that only part of any exchange event is highlighted. However, this partial detection imposes certain limitations when the technique is applied to fundamental studies with primary aberrations, particularly at higher doses, when Complex exchanges are present. Some of these limitations are discussed in this paper.

Mesh：

Year:  1994        PMID： 7513815     DOI： 10.1016/0027-5107(94)90308-5

Source DB:  PubMed          Journal:  Mutat Res        ISSN： 0027-5107            Impact factor:   2.433


  10 in total

1.  Analysis of X-ray-induced aberrations in human chromosome 5 using high-resolution multicolour banding FISH (mBAND).

Authors:  C Johannes; I Chudoba; G Obe
Journal:  Chromosome Res       Date:  1999       Impact factor: 5.239

Review 2.  Current status of biodosimetry based on standard cytogenetic methods.

Authors:  Marcela Maria Pereira de Lemos Pinto; Neyliane Frassinetti Gonçalves Santos; Ademir Amaral
Journal:  Radiat Environ Biophys       Date:  2010-07-09       Impact factor: 1.925

3.  Familial complex chromosome rearrangement ascertained by in situ hybridisation.

Authors:  C Fuster; L Miguez; R Miró; M A Rigola; A Perez; J Egozcue
Journal:  J Med Genet       Date:  1997-02       Impact factor: 6.318

4.  Detecting 'hidden' exchange events within X-ray-induced aberrations using multicolour chromosome paints.

Authors:  P J Simpson; J R Savage
Journal:  Chromosome Res       Date:  1995-01       Impact factor: 5.239

5.  Detection of Inter-chromosomal Stable Aberrations by Multiple Fluorescence In Situ Hybridization (mFISH) and Spectral Karyotyping (SKY) in Irradiated Mice.

Authors:  Rupak Pathak; Igor Koturbash; Martin Hauer-Jensen
Journal:  J Vis Exp       Date:  2017-01-11       Impact factor: 1.355

6.  Kinase inhibitors increase individual radiation sensitivity in normal cells of cancer patients.

Authors:  Tina Jost; Barbara Schuster; Lucie Heinzerling; Thomas Weissmann; Rainer Fietkau; Luitpold V Distel; Markus Hecht
Journal:  Strahlenther Onkol       Date:  2022-04-26       Impact factor: 4.033

7.  Clinical, molecular- and cytogenetic analysis of a case of severe radio-sensitivity.

Authors:  K M Greulich-Bode; F Zimmermann; W-U Müller; B Pakisch; M Molls; F Würschmidt
Journal:  Curr Genomics       Date:  2012-09       Impact factor: 2.236

8.  Biological Effectiveness of Accelerated Protons for Chromosome Exchanges.

Authors:  Kerry A George; Megumi Hada; Francis A Cucinotta
Journal:  Front Oncol       Date:  2015-10-19       Impact factor: 6.244

9.  Rate of individuals with clearly increased radiosensitivity rise with age both in healthy individuals and in cancer patients.

Authors:  Barbara Schuster; Anna Ellmann; Theresa Mayo; Judith Auer; Matthias Haas; Markus Hecht; Rainer Fietkau; Luitpold V Distel
Journal:  BMC Geriatr       Date:  2018-05-04       Impact factor: 3.921

10.  Is in vivo and ex vivo irradiation equally reliable for individual Radiosensitivity testing by three colour fluorescence in situ hybridization?

Authors:  Theresa Mayo; Marlen Haderlein; Barbara Schuster; Anna Wiesmüller; Christian Hummel; Maximilian Bachl; Manfred Schmidt; Rainer Fietkau; Luitpold Distel
Journal:  Radiat Oncol       Date:  2019-12-31       Impact factor: 3.481
  10 in total

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