Literature DB >> 7513811

Induction of sister-chromatid exchanges by AluI, DNase I, benzon nuclease and bleomycin in Chinese hamster ovary (CHO) cells.

G Obe1, C Schunck, C Johannes.   

Abstract

Various endonucleases (AluI, DNase I, benzon nuclease) and bleomycin induce sister-chromatid exchanges (SCE) in Chinese hamster ovary (CHO) cells. The frequencies of SCE are elevated in cells with chromosome-type aberrations, only slightly elevated in cells with chromatid exchanges, and in the control range in cells without chromosomal aberrations. These data indicate that SCE are produced when DNA breaks induced in G1 are either not repaired or misrepaired.

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Year:  1994        PMID： 7513811     DOI： 10.1016/0027-5107(94)90305-0

Source DB:  PubMed          Journal:  Mutat Res        ISSN： 0027-5107            Impact factor:   2.433


  4 in total

1.  X-irradiation of G1 CHO cells induces SCE which are both true and false in BrdU-substituted cells but only false in biotin-dUTP-substituted cells.

Authors:  E Bruckmann; A Wojcik; G Obe
Journal:  Chromosome Res       Date:  1999       Impact factor: 5.239

2.  Induction of homologous recombination following in utero exposure to DNA-damaging agents.

Authors:  Bijal Karia; Jo Ann Martinez; Alexander J R Bishop
Journal:  DNA Repair (Amst)       Date:  2013-09-10

3.  On the importance of DNA strand breaks as the first event to initiate sister chromatid exchange (SCE): experiments with restriction endonuclease BglI.

Authors:  T Ortiz; J Piñero; F Cortés
Journal:  Chromosome Res       Date:  1996-11       Impact factor: 5.239

4.  A hyperactive piggyBac transposase for mammalian applications.

Authors:  Kosuke Yusa; Liqin Zhou; Meng Amy Li; Allan Bradley; Nancy L Craig
Journal:  Proc Natl Acad Sci U S A       Date:  2011-01-04       Impact factor: 11.205
  4 in total

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