| Literature DB >> 7509918 |
M A Ghoneim1, T Yamamoto, S Hirose, T Nagasawa, H Hagiwara.
Abstract
The ETB receptor has been found to be predominantly expressed in the vascular endothelium of various bovine tissues by immunostaining with a highly specific antiserum that does not cross-react with ETA. The tissues examined include the lung, trachea, kidney, adrenal gland, pituitary gland, and cerebellum. The wide-spread localization of ETB in the endothelial lining suggests that there is an ETB-mediated autocrine system of endothelin, which plays an important role in regulation of the functions of endothelial cells.Entities:
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Year: 1993 PMID: 7509918 DOI: 10.1097/00005344-199322008-00030
Source DB: PubMed Journal: J Cardiovasc Pharmacol ISSN: 0160-2446 Impact factor: 3.105