| Literature DB >> 7509316 |
C M Mink1, C H O'Brien, S Wassilak, A Deforest, B D Meade.
Abstract
Elevated agglutinin titers have been shown to correlate with protection from disease following whole-cell pertussis vaccination, but the isotype and antigen specificity of human agglutinating antibodies is unknown. In 13 immunoassays, immunoglobulin G antifimbria antibodies had the strongest correlation with agglutinin titers following culture-proven infection with Bordetella pertussis (R' = 0.79; P < 0.0001) and following whole-cell pertussis vaccination (R' = 0.87, P < 0.0001).Entities:
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Year: 1994 PMID: 7509316 PMCID: PMC186231 DOI: 10.1128/iai.62.3.1118-1120.1994
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441