Literature DB >> 7509004

Redesignation of the RNase D activity associated with retroviral reverse transcriptase as RNase H.

Z Hostomsky1, S H Hughes, S P Goff, S F Le Grice.   

Abstract

In the presence of Mn2+, reverse transcriptase of both human immunodeficiency virus and murine leukemia virus hydrolyzes duplex RNA. However, designating this novel activity RNase D conflicts with Escherichia coli RNase D, which participates in tRNA processing. On the basis of its location in the RNase H domain, we propose that this novel retroviral activity be redesignated RNase H*.

Entities:  

Mesh：

Substances：

Year:  1994        PMID： 7509004      PMCID： PMC236660     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  8 in total

1.  Characterization of the double stranded RNA dependent RNase activity associated with recombinant reverse transcriptases.

Authors:  H Ben-Artzi; E Zeelon; S F Le-Grice; M Gorecki; A Panet
Journal:  Nucleic Acids Res       Date:  1992-10-11       Impact factor: 16.971

2.  Linker insertion mutagenesis of the human immunodeficiency virus reverse transcriptase expressed in bacteria: definition of the minimal polymerase domain.

Authors:  V R Prasad; S P Goff
Journal:  Proc Natl Acad Sci U S A       Date:  1989-05       Impact factor: 11.205

3.  Rapid purification of homodimer and heterodimer HIV-1 reverse transcriptase by metal chelate affinity chromatography.

Authors:  S F Le Grice; F Grüninger-Leitch
Journal:  Eur J Biochem       Date:  1990-01-26

Review 4.  Ribonuclease multiplicity, diversity, and complexity.

Authors:  M P Deutscher
Journal:  J Biol Chem       Date:  1993-06-25       Impact factor: 5.157

5.  Mutational analysis of the DNA polymerase and ribonuclease H activities of human immunodeficiency virus type 2 reverse transcriptase expressed in Escherichia coli.

Authors:  A Hizi; R Tal; S H Hughes
Journal:  Virology       Date:  1991-01       Impact factor: 3.616

6.  Nuclease activities of Moloney murine leukemia virus reverse transcriptase. Mutants with altered substrate specificities.

Authors:  S W Blain; S P Goff
Journal:  J Biol Chem       Date:  1993-11-05       Impact factor: 5.157

7.  RNase D, a reported new activity associated with HIV-1 reverse transcriptase, displays the same cleavage specificity as Escherichia coli RNase III.

Authors:  Z Hostomsky; G O Hudson; S Rahmati; Z Hostomska
Journal:  Nucleic Acids Res       Date:  1992-11-11       Impact factor: 16.971

8.  Double-stranded RNA-dependent RNase activity associated with human immunodeficiency virus type 1 reverse transcriptase.

Authors:  H Ben-Artzi; E Zeelon; M Gorecki; A Panet
Journal:  Proc Natl Acad Sci U S A       Date:  1992-02-01       Impact factor: 11.205
  8 in total
  9 in total

1.  NMR structure of the chimeric hybrid duplex r(gcaguggc).r(gcca)d(CTGC) comprising the tRNA-DNA junction formed during initiation of HIV-1 reverse transcription.

Authors:  T Szyperski; M Götte; M Billeter; E Perola; L Cellai; H Heumann; K Wüthrich
Journal:  J Biomol NMR       Date:  1999-04       Impact factor: 2.835

2.  The reverse transcriptase of the Tf1 retrotransposon has a specific novel activity for generating the RNA self-primer that is functional in cDNA synthesis.

Authors:  Amnon Hizi
Journal:  J Virol       Date:  2008-08-27       Impact factor: 5.103

3.  Reversion of a Moloney murine leukemia virus RNase H mutant at a second site restores enzyme function and infectivity.

Authors:  S W Blain; W A Hendrickson; S P Goff
Journal:  J Virol       Date:  1995-08       Impact factor: 5.103

4.  An unusual mechanism of self-primed reverse transcription requires the RNase H domain of reverse transcriptase to cleave an RNA duplex.

Authors:  H L Levin
Journal:  Mol Cell Biol       Date:  1996-10       Impact factor: 4.272

5.  Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract RNA:DNA.

Authors:  S G Sarafianos; K Das; C Tantillo; A D Clark; J Ding; J M Whitcomb; P L Boyer; S H Hughes; E Arnold
Journal:  EMBO J       Date:  2001-03-15       Impact factor: 11.598

6.  Cleavage of double-stranded RNA by RNase HI from a thermoacidophilic archaeon, Sulfolobus tokodaii 7.

Authors:  Naoto Ohtani; Hiroshi Yanagawa; Masaru Tomita; Mitsuhiro Itaya
Journal:  Nucleic Acids Res       Date:  2004-11-01       Impact factor: 16.971

7.  Mutational analysis of the reverse transcriptase and ribonuclease H domains of the human foamy virus.

Authors:  D Kögel; M Aboud; R M Flügel
Journal:  Nucleic Acids Res       Date:  1995-07-25       Impact factor: 16.971

Review 8.  Ribonuclease H: properties, substrate specificity and roles in retroviral reverse transcription.

Authors:  James J Champoux; Sharon J Schultz
Journal:  FEBS J       Date:  2009-02-18       Impact factor: 5.542

9.  HIV-1 reverse transcriptase-associated RNase H cleaves RNA/RNA in arrested complexes: implications for the mechanism by which RNase H discriminates between RNA/RNA and RNA/DNA.

Authors:  M Götte; S Fackler; T Hermann; E Perola; L Cellai; H J Gross; S F Le Grice; H Heumann
Journal:  EMBO J       Date:  1995-02-15       Impact factor: 11.598
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.