| Literature DB >> 7506810 |
R Yamanaka1, R Tanaka, S Yoshida.
Abstract
The expression of the intercellular adhesion molecule-1 (ICAM-1) and neural cell adhesion molecule (NCAM) by glioma cell lines was investigated. The effects of interferon (IFN)-gamma or irradiation on the expression was also assessed. Two glioma cell lines showed more than 75% NCAM-positive cells. After treatment with IFN-gamma or irradiation, another three cell lines were induced to show more than 50% positive cells. Three glioma cell lines showed more than 50% ICAM-1-positive cells. After treatment with IFN-gamma, another two cell lines were induced to show more than 50% positive cells. After treatment with irradiation, one more cell line was induced to show more than 50% positive cells. ICAM-1 and NCAM expression by glioma cell lines is susceptible to modulation by IFN-gamma or irradiation.Entities:
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Year: 1993 PMID: 7506810 DOI: 10.2176/nmc.33.749
Source DB: PubMed Journal: Neurol Med Chir (Tokyo) ISSN: 0470-8105 Impact factor: 1.742