Tolerability of nimesulide and ketoprofen in paediatric patients with traumatic or surgical fractures.

The anti-inflammatory and analgesic activities of orally administered nimesulide and ketoprofen were assessed in a group of 71 paediatric patients (aged 7 to 14 years) with orthopaedic disorders. Both drugs had similar efficacy. The greatest advantage of nimesulide was its better tolerability: only 3 nimesulide-treated patients (8.6%) experienced side effects related to the drug, compared with 12 (33%) of the ketoprofen-treated children.

RCT Entities:   Population Interventions Outcomes