Literature DB >> 7506160

Comparison of nimesulide and diclofenac in the prevention and treatment of painful inflammatory postoperative complications of general surgery.

G Ramella1, V Costagli, M Vetere, C Capra, G Casella, A Sogni, I Scaricabarozzi.   

Abstract

In a double-blind study, 40 patients scheduled for saphenectomy or inguinal hernioplasty were randomly assigned to treatment with nimesulide (200mg 3 times daily) or diclofenac (100mg 3 times daily) administered rectally. Therapy with either drug resulted in significantly less pain, oedema and hyperaemia, and resolution of mild fever. No adverse reactions attributable to treatment were observed.

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Year:  1993        PMID： 7506160     DOI： 10.2165/00003495-199300461-00038

Source DB:  PubMed          Journal:  Drugs        ISSN： 0012-6667            Impact factor:   9.546


  5 in total

1.  [Clinical efficacy of nimesulide compared to diclofenac sodium in the prevention and treatment of postoperative pain-inflammation symptomatology].

Authors:  G Stefanoni; F Saccomanno; I Scaricabarozzi; G Volontieri; L Persiani; A Boselli; P Beretta; M Giroda
Journal:  Minerva Chir       Date:  1990-12       Impact factor: 1.000

2.  [A clinical study of the therapeutic activity and tolerance of nimesulide in a suppository formulation in oral medicine].

Authors:  E Bucci; M D Mignogna; I Scaricabarozzi; P Bucci; L Lo Muzio; R Trezzani
Journal:  Minerva Stomatol       Date:  1990-10

3.  [Clinical study of the efficacy and tolerability of nimesulide in suppositories compared to flurbiprofen in gynecology].

Authors:  C Montoneri; A Garofalo; S Iurato; I Scaricabarozzi; R Trezzani
Journal:  Minerva Ginecol       Date:  1990-10

Review 4.  Nimesulide. A preliminary review of its pharmacological properties and therapeutic efficacy in inflammation and pain states.

Authors:  A Ward; R N Brogden
Journal:  Drugs       Date:  1988-12       Impact factor: 9.546

5.  [The nimesulide treatment of inflammation and posttraumatic pain in maxillofacial surgery. A controlled study versus flurbiprofen].

Authors:  G Scolari; G Vargiu; I Scaricabarozzi
Journal:  Minerva Stomatol       Date:  1990-12
  5 in total
  1 in total

Review 1.  Nimesulide. An update of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy.

Authors:  R Davis; R N Brogden
Journal:  Drugs       Date:  1994-09       Impact factor: 9.546
  1 in total

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