| Literature DB >> 7504987 |
P M Deen1, D O Weghuis, A Geurs van Kessel, B Wieringa, C H van Os.
Abstract
The chromosomal localization of the gene encoding aquaporin 1 (previously called CHIP28), which acts as a water channel in erythrocytes and in the renal proximal tubules and descending limbs of Henle, was determined. Southern blot hybridizations on chromosomal DNA of a panel of 25 different human x rodent hybrid cell lines localized the aquaporin 1 gene to human chromosome 7. Additionally, in situ hybridization on R-banded metaphase chromosomes sublocalized the aquaporin 1 gene (AQP1) to 7p15-->p14, and some sequence-tagged sites in this region were identified.Entities:
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Year: 1994 PMID： 7504987 DOI： 10.1159/000133639
Source DB: PubMed Journal: Cytogenet Cell Genet ISSN： 0301-0171