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Literature DB >> 7504985

Hypothyroidism and arthritis during interferon therapy.

Abstract

The development of autoantibodies during interferon therapy is frequent, but clinical symptoms of autoimmune disease are uncommon. We report on a female patient who developed arthritis with strongly positive antinuclear factor (ANA) and autoimmune thyroiditis while being treated with alpha 2b interferon (IFN) for chronic myelocytic leukaemia (CML). The arthritis subsided promptly after discontinuation of IFN and initiation of nonsteroidal anti-inflammatory drugs.

Entities: Disease Gene Species

Mesh：

Substances：

Year: 1993 PMID： 7504985 DOI： 10.1007/bf02231591

Source DB: PubMed Journal: Clin Rheumatol ISSN： 0770-3198 Impact factor: 2.980

12 in total

1. Alpha-interferon-induced nodular rheumatoid arthritis in renal cell carcinoma.

Authors: Y Ueno; T Sohma
Journal: Ann Intern Med Date: 1992-08-01 Impact factor: 25.391

2. A case of arthropathy and hypothyroidism during recombinant alpha-interferon therapy.

Authors: S Maccari; C Bassi; A G Giovannini; A C Plancher
Journal: Clin Rheumatol Date: 1991-12 Impact factor: 2.980

3. Autoimmunity after alpha-interferon therapy for malignant carcinoid tumors.

Authors: L E Rönnblom; G V Alm; K E Oberg
Journal: Ann Intern Med Date: 1991-08-01 Impact factor: 25.391

4. Alpha-interferon and immune hemolytic anemia.

Authors: L P Akard; R Hoffman; L Elias; J H Saiers
Journal: Ann Intern Med Date: 1986-08 Impact factor: 25.391

5. Immune thrombocytopenia after alpha-interferon therapy in patients with cancer.

Authors: E A Abdi; P M Venner
Journal: JAMA Date: 1986-04-11 Impact factor: 56.272

6. Treatment of chronic type B hepatitis with recombinant alpha-interferon induces autoantibodies not specific for autoimmune chronic hepatitis.

Authors: W J Mayet; G Hess; G Gerken; S Rossol; R Voth; M Manns; K H Meyer zum Büschenfelde
Journal: Hepatology Date: 1989-07 Impact factor: 17.425

7. Exacerbation of symptoms of autoimmune disease in patients receiving alpha-interferon therapy.

Authors: K C Conlon; W J Urba; J W Smith; R G Steis; D L Longo; J W Clark
Journal: Cancer Date: 1990-05-15 Impact factor: 6.860

8. Interferon-induced aplasia: evidence for T-cell-mediated suppression of hematopoiesis and recovery after treatment with horse antihuman thymocyte globulin.

Authors: K F Mangan; B Zidar; R K Shadduck; Z Zeigler; A Winkelstein
Journal: Am J Hematol Date: 1985-08 Impact factor: 10.047

Hypothyroidism and arthritis during interferon therapy.

1. Alpha-interferon-induced nodular rheumatoid arthritis in renal cell carcinoma.

2. A case of arthropathy and hypothyroidism during recombinant alpha-interferon therapy.

3. Autoimmunity after alpha-interferon therapy for malignant carcinoid tumors.

4. Alpha-interferon and immune hemolytic anemia.

5. Immune thrombocytopenia after alpha-interferon therapy in patients with cancer.

6. Treatment of chronic type B hepatitis with recombinant alpha-interferon induces autoantibodies not specific for autoimmune chronic hepatitis.

7. Exacerbation of symptoms of autoimmune disease in patients receiving alpha-interferon therapy.

8. Interferon-induced aplasia: evidence for T-cell-mediated suppression of hematopoiesis and recovery after treatment with horse antihuman thymocyte globulin.

9. Development of systemic lupus erythematosus after interferon therapy for chronic myelogenous leukemia.

Review 10. Clinical toxicity of interferons in cancer patients: a review.

1. Autoimmune hepatitis and thyroiditis associated with rifampin and pyrazinamide prophylaxis: an unusual reaction.

Review 2. [Interferon therapy and autoimmunity].