Literature DB >> 7504932

Stratification of the channel domain in neurotransmitter receptors.

D Bertrand1, J L Galzi, A Devillers-Thiéry, S Bertrand, J P Changeux.   

Abstract

Analyses of the ionic pore of ligand-gated ion channels at the amino acid level reveal a structural and functional stratification of the M2 channel domain. Mutations in the equatorial and outer regions affect channel gating, whereas mutations of other amino acid rings alter ionic permeability or selectivity.

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Substances：

Year:  1993        PMID： 7504932     DOI： 10.1016/0955-0674(93)90141-c

Source DB:  PubMed          Journal:  Curr Opin Cell Biol        ISSN： 0955-0674            Impact factor:   8.382


  20 in total

Review 1.  Inherited and experimentally induced changes in gating kinetics of muscle nicotinic acetylcholine receptor.

Authors:  C Bouzat; F J Barrantes
Journal:  J Mol Neurosci       Date:  1999 Aug-Oct       Impact factor: 3.444

Review 2.  Molecular investigations on the nicotinic acetylcholine receptor: conformational mapping and dynamic exploration using photoaffinity labeling.

Authors:  F Kotzyba-Hibert; T Grutter; M Goeldner
Journal:  Mol Neurobiol       Date:  1999-08       Impact factor: 5.590

3.  Key roles of hydrophobic rings of TM2 in gating of the alpha9alpha10 nicotinic cholinergic receptor.

Authors:  Paola V Plazas; María J De Rosa; María E Gomez-Casati; Miguel Verbitsky; Noelia Weisstaub; Eleonora Katz; Cecilia Bouzat; Ana Belén Elgoyhen
Journal:  Br J Pharmacol       Date:  2005-08       Impact factor: 8.739

Review 4.  Functional architecture of the nicotinic acetylcholine receptor: a prototype of ligand-gated ion channels.

Authors:  A Devillers-Thiéry; J L Galzi; J L Eiselé; S Bertrand; D Bertrand; J P Changeux
Journal:  J Membr Biol       Date:  1993-11       Impact factor: 1.843

5.  Molecular evolution of the nicotinic acetylcholine receptor: an example of multigene family in excitable cells.

Authors:  N Le Novère; J P Changeux
Journal:  J Mol Evol       Date:  1995-02       Impact factor: 2.395

6.  The pore domain of the nicotinic acetylcholine receptor: molecular modeling, pore dimensions, and electrostatics.

Authors:  R Sankararamakrishnan; C Adcock; M S Sansom
Journal:  Biophys J       Date:  1996-10       Impact factor: 4.033

Review 7.  The acetylcholine receptor ligand-gated channel as a molecular target of disease and therapeutic agents.

Authors:  F J Barrantes
Journal:  Neurochem Res       Date:  1997-04       Impact factor: 3.996

Review 8.  Neuronal Nicotinic Acetylcholine Receptor Structure and Function and Response to Nicotine.

Authors:  John A Dani
Journal:  Int Rev Neurobiol       Date:  2015-08-21       Impact factor: 3.230

Review 9.  The neuronal nicotinic acetylcholine receptor in some hereditary epilepsies.

Authors:  F J Barrantes; E Aztiria; M B Rauschemberger; A Vasconsuelo
Journal:  Neurochem Res       Date:  2000-05       Impact factor: 3.996

10.  Single particle tracking of alpha7 nicotinic AChR in hippocampal neurons reveals regulated confinement at glutamatergic and GABAergic perisynaptic sites.

Authors:  Thomas Bürli; Kristin Baer; Helge Ewers; Corinne Sidler; Christian Fuhrer; Jean-Marc Fritschy
Journal:  PLoS One       Date:  2010-07-09       Impact factor: 3.240
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