Literature DB >> 7504359

The TiPS/TINS lecture: the molecular biology of mammalian glutamate receptor channels.

P H Seeburg1.   

Abstract

In native brain membranes the principal excitatory neurotransmitter L-glutamate activates cation-conducting channels with distinct biophysical and pharmacological properties. Molecular cloning has revealed the existence of 16 channel subunits that can assemble in homomeric or heteromeric configurations in vitro to form receptor channels with disparate functional properties. This review describes the different channel types obtained by recombinant means and the genetic mechanisms controlling the expression of functionally important channel structures.

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Year:  1993        PMID： 7504359     DOI： 10.1016/0165-6147(93)90047-N

Source DB:  PubMed          Journal:  Trends Pharmacol Sci        ISSN： 0165-6147            Impact factor:   14.819


  43 in total

Review 1.  General anaesthetic actions on ligand-gated ion channels.

Authors:  M D Krasowski; N L Harrison
Journal:  Cell Mol Life Sci       Date:  1999-08-15       Impact factor: 9.261

2.  Caspase-mediated degradation of AMPA receptor subunits: a mechanism for preventing excitotoxic necrosis and ensuring apoptosis.

Authors:  G W Glazner; S L Chan; C Lu; M P Mattson
Journal:  J Neurosci       Date:  2000-05-15       Impact factor: 6.167

3.  Neutrophil depletion after subarachnoid hemorrhage improves memory via NMDA receptors.

Authors:  Jose Javier Provencio; Valerie Swank; Haiyan Lu; Sylvain Brunet; Selva Baltan; Rohini V Khapre; Himabindu Seerapu; Olga N Kokiko-Cochran; Bruce T Lamb; Richard M Ransohoff
Journal:  Brain Behav Immun       Date:  2016-02-09       Impact factor: 7.217

4.  Stoichiometry of recombinant N-methyl-D-aspartate receptor channels inferred from single-channel current patterns.

Authors:  L S Premkumar; A Auerbach
Journal:  J Gen Physiol       Date:  1997-11       Impact factor: 4.086

5.  pH-dependent inhibition of kainate receptors by zinc.

Authors:  David D Mott; Morris Benveniste; Raymond J Dingledine
Journal:  J Neurosci       Date:  2008-02-13       Impact factor: 6.167

6.  Volatile anesthetics inhibit NMDA-stimulated 45Ca uptake by rat brain microvesicles.

Authors:  R S Aronstam; D C Martin; R L Dennison
Journal:  Neurochem Res       Date:  1994-12       Impact factor: 3.996

7.  Characterization of two central AMPA-preferring receptors having distinct location, function and pharmacology.

Authors:  A Pittaluga; S Thellung; G Maura; M Raiteri
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1994-06       Impact factor: 3.000

8.  Impaired social behaviors and minimized oxytocin signaling of the adult mice deficient in the N-methyl-d-aspartate receptor GluN3A subunit.

Authors:  Jin Hwan Lee; James Ya Zhang; Zheng Zachory Wei; Shan Ping Yu
Journal:  Exp Neurol       Date:  2018-03-16       Impact factor: 5.330

9.  Changes in AMPA receptor-spliced variant expression and shift in AMPA receptor spontaneous desensitization pharmacology during cerebellar granule cell maturation in vitro.

Authors:  P Longone; F Impagnatiello; J M Mienville; E Costa; A Guidotti
Journal:  J Mol Neurosci       Date:  1998-08       Impact factor: 3.444

Review 10.  Trends in the development of new antidepressants. Is there a light at the end of the tunnel?

Authors:  Pal Pacher; Valeria Kecskemeti
Journal:  Curr Med Chem       Date:  2004-04       Impact factor: 4.530
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