Literature DB >> 7504352

The dynamic clamp: artificial conductances in biological neurons.

A A Sharp1, M B O'Neil, L F Abbott, E Marder.   

Abstract

The dynamic clamp is a novel method that uses computer simulation to introduce conductances into biological neurons. This method can be used to study the role of various conductances in shaping the activity of single neurons, or neurons within networks. The dynamic clamp can also be used to form circuits from previously unconnected neurons. This approach makes computer simulation an interactive experimental tool, and will be useful in many applications where the role of synaptic strengths and intrinsic properties in neuronal and network dynamics is of interest.

Mesh：

Year:  1993        PMID： 7504352     DOI： 10.1016/0166-2236(93)90004-6

Source DB:  PubMed          Journal:  Trends Neurosci        ISSN： 0166-2236            Impact factor:   13.837


  107 in total

1.  Synaptic control of spiking in cerebellar Purkinje cells: dynamic current clamp based on model conductances.

Authors:  D Jaeger; J M Bower
Journal:  J Neurosci       Date:  1999-07-15       Impact factor: 6.167

2.  Coordination of fast and slow rhythmic neuronal circuits.

Authors:  M Bartos; Y Manor; F Nadim; E Marder; M P Nusbaum
Journal:  J Neurosci       Date:  1999-08-01       Impact factor: 6.167

3.  Global structure, robustness, and modulation of neuronal models.

Authors:  M S Goldman; J Golowasch; E Marder; L F Abbott
Journal:  J Neurosci       Date:  2001-07-15       Impact factor: 6.167

Review 4.  Novel neuronal and astrocytic mechanisms in thalamocortical loop dynamics.

Authors:  Vincenzo Crunelli; Kate L Blethyn; David W Cope; Stuart W Hughes; H Rheinallt Parri; Jonathan P Turner; Tibor I Tòth; Stephen R Williams
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2002-12-29       Impact factor: 6.237

5.  Enhancement of signal-to-noise ratio and phase locking for small inputs by a low-threshold outward current in auditory neurons.

Authors:  Gytis Svirskis; Vibhakar Kotak; Dan H Sanes; John Rinzel
Journal:  J Neurosci       Date:  2002-12-15       Impact factor: 6.167

6.  Modulators with convergent cellular actions elicit distinct circuit outputs.

Authors:  A M Swensen; E Marder
Journal:  J Neurosci       Date:  2001-06-01       Impact factor: 6.167

7.  Subthreshold outward currents enhance temporal integration in auditory neurons.

Authors:  Gytis Svirskis; Ramana Dodla; John Rinzel
Journal:  Biol Cybern       Date:  2003-11-28       Impact factor: 2.086

8.  Kv3 potassium conductance is necessary and kinetically optimized for high-frequency action potential generation in hippocampal interneurons.

Authors:  Cheng-Chang Lien; Peter Jonas
Journal:  J Neurosci       Date:  2003-03-15       Impact factor: 6.167

9.  The functional consequences of changes in the strength and duration of synaptic inputs to oscillatory neurons.

Authors:  Astrid A Prinz; Vatsala Thirumalai; Eve Marder
Journal:  J Neurosci       Date:  2003-02-01       Impact factor: 6.167

10.  Pyramidal cell communication within local networks in layer 2/3 of rat neocortex.

Authors:  Carl Holmgren; Tibor Harkany; Björn Svennenfors; Yuri Zilberter
Journal:  J Physiol       Date:  2003-06-17       Impact factor: 5.182
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