Literature DB >> 7502544

The effect of graded ascorbic acid intake on the activity of GSH-Px in the liver of female guinea pigs.

Z Kováciková1, E Ginter, A Madaric.   

Abstract

Differing antioxidant potentials created by graded ascorbic acid supplementation (1, 10, 100 mg per animal daily) evoked changes in the level of glutathione peroxidase activity and lipid peroxides in the liver of female guinea pigs. The group with the lowest ascorbic acid intake (1 mg) had the lowest activity of glutathione peroxidase and the highest level of lipid peroxides. The two other groups (10 and 100 mg) showed enhancement of glutathione peroxidase activity and decline in lipid peroxides. There was no difference between the groups with 10 and 100 mg ascorbic acid intake.

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Year:  1995        PMID: 7502544     DOI: 10.1007/bf01623161

Source DB:  PubMed          Journal:  Z Ernahrungswiss        ISSN: 0044-264X


  12 in total

1.  Glutathione peroxidase activity of glutathione-s-transferases purified from rat liver.

Authors:  J R Prohaska; H E Ganther
Journal:  Biochem Biophys Res Commun       Date:  1976-05-23       Impact factor: 3.575

2.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

3.  Glutathione peroxidase activity in selenium-deficient rat liver.

Authors:  R A Lawrence; R F Burk
Journal:  Biochem Biophys Res Commun       Date:  1976-08-23       Impact factor: 3.575

4.  Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction.

Authors:  H Ohkawa; N Ohishi; K Yagi
Journal:  Anal Biochem       Date:  1979-06       Impact factor: 3.365

5.  Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase.

Authors:  D E Paglia; W N Valentine
Journal:  J Lab Clin Med       Date:  1967-07

6.  The influence of ascorbic acid on lipid peroxidation in guinea pigs intoxicated with cadmium.

Authors:  A Hudecová; E Ginter
Journal:  Food Chem Toxicol       Date:  1992-12       Impact factor: 6.023

7.  Lipoperoxides in plasma as measured by liquid-chromatographic separation of malondialdehyde-thiobarbituric acid adduct.

Authors:  S H Wong; J A Knight; S M Hopfer; O Zaharia; C N Leach; F W Sunderman
Journal:  Clin Chem       Date:  1987-02       Impact factor: 8.327

8.  Effect of dietary vitamin C and catalase inhibition of antioxidants and molecular markers of oxidative damage in guinea pigs.

Authors:  S Cadenas; C Rojas; R Pérez-Campo; M López-Torres; G Barja
Journal:  Free Radic Res       Date:  1994-08

9.  Glutathione blood levels and other oxidant defense indices in men fed diets low in vitamin C.

Authors:  S M Henning; J Z Zhang; R W McKee; M E Swendseid; R A Jacob
Journal:  J Nutr       Date:  1991-12       Impact factor: 4.798

10.  Tissue levels and optimum dosage of vitamin C in guinea pigs.

Authors:  E Ginter; P Bobek; D Vargová
Journal:  Nutr Metab       Date:  1979       Impact factor: 4.169

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