Literature DB >> 7502067

The centromere: hub of chromosomal activities.

A F Pluta1, A M Mackay, A M Ainsztein, I G Goldberg, W C Earnshaw.   

Abstract

Centromeres are the structures that direct eukaryotic chromosome segregation in mitosis and meiosis. There are two major classes of centromeres. Point centromeres, found in the budding yeasts, are compact loci whose constituent proteins are now beginning to yield to biochemical analysis. Regional centromeres, best described in the fission yeast Schizosaccharomyces pombe, encompass many kilobases of DNA and are packaged into heterochromatin. Their associated proteins are as yet poorly understood. In addition to providing the site for microtubule attachment, centromeres also have an important role in checkpoint regulation during mitosis.

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Year:  1995        PMID： 7502067     DOI： 10.1126/science.270.5242.1591

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  139 in total

1.  Mapping of a human centromere onto the DNA by topoisomerase II cleavage.

Authors:  G Floridia; A Zatterale; O Zuffardi; C Tyler-Smith
Journal:  EMBO Rep       Date:  2000-12       Impact factor: 8.807

2.  A maize homolog of mammalian CENPC is a constitutive component of the inner kinetochore.

Authors:  R K Dawe; L M Reed; H G Yu; M G Muszynski; E N Hiatt
Journal:  Plant Cell       Date:  1999-07       Impact factor: 11.277

3.  Specific destruction of kinetochore protein CENP-C and disruption of cell division by herpes simplex virus immediate-early protein Vmw110.

Authors:  R D Everett; W C Earnshaw; J Findlay; P Lomonte
Journal:  EMBO J       Date:  1999-03-15       Impact factor: 11.598

4.  CENP-H, a constitutive centromere component, is required for centromere targeting of CENP-C in vertebrate cells.

Authors:  T Fukagawa; Y Mikami; A Nishihashi; V Regnier; T Haraguchi; Y Hiraoka; N Sugata; K Todokoro; W Brown; T Ikemura
Journal:  EMBO J       Date:  2001-08-15       Impact factor: 11.598

5.  Creation and characterization of temperature-sensitive CENP-C mutants in vertebrate cells.

Authors:  T Fukagawa; V Regnier; T Ikemura
Journal:  Nucleic Acids Res       Date:  2001-09-15       Impact factor: 16.971

6.  Partially inverted tandem repeat isolated from pericentric region of chicken chromosome 8.

Authors:  Xiaofei Wang; Juan Li; Frederick C Leung
Journal:  Chromosome Res       Date:  2002       Impact factor: 5.239

7.  Chromosomal G-dark bands determine the spatial organization of centromeric heterochromatin in the nucleus.

Authors:  C Carvalho; H M Pereira; J Ferreira; C Pina; D Mendonça; A C Rosa; M Carmo-Fonseca
Journal:  Mol Biol Cell       Date:  2001-11       Impact factor: 4.138

8.  The DNA sequence of chromosome I of an African trypanosome: gene content, chromosome organisation, recombination and polymorphism.

Authors:  Neil Hall; Matthew Berriman; Nicola J Lennard; Barbara R Harris; Christiane Hertz-Fowler; Emmanuelle N Bart-Delabesse; Caroline S Gerrard; Rebecca J Atkin; Andrew J Barron; Sharen Bowman; Sarah P Bray-Allen; Frédéric Bringaud; Louise N Clark; Craig H Corton; Ann Cronin; Robert Davies; Jonathon Doggett; Audrey Fraser; Eric Grüter; Sarah Hall; A David Harper; Mike P Kay; Vanessa Leech; Rebecca Mayes; Claire Price; Michael A Quail; Ester Rabbinowitsch; Christopher Reitter; Kim Rutherford; Jürgen Sasse; Sarah Sharp; Ratna Shownkeen; Annette MacLeod; Sonya Taylor; Alison Tweedie; C Michael R Turner; Andrew Tait; Keith Gull; Bart Barrell; Sara E Melville
Journal:  Nucleic Acids Res       Date:  2003-08-15       Impact factor: 16.971

Review 9.  Centromere DNA, proteins and kinetochore assembly in vertebrate cells.

Authors:  Tatsuo Fukagawa
Journal:  Chromosome Res       Date:  2004       Impact factor: 5.239

10.  Structure of the chromosome VII centromere region in Neurospora crassa: degenerate transposons and simple repeats.

Authors:  E B Cambareri; R Aisner; J Carbon
Journal:  Mol Cell Biol       Date:  1998-09       Impact factor: 4.272
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