Literature DB >> 7501659

CRF administered to pregnant rats alters offspring behavior and morphology.

M T Williams1, M B Hennessy, H N Davis.   

Abstract

Pregnant rats injected with 20 micrograms of corticotropin-releasing factor (CRF) from day 14 through 21 gained less weight during gestation than did saline-injected controls. The offspring of CRF-injected females differed from the offspring of control females in several ways: males and females weighed less during the first 2 weeks of life, males had shorter anogenital distances at birth, and males and females emitted more ultrasonic vocalizations during isolation in tests at 6 and 14 days of age. These effects are similar to those that have been observed following exposure of pregnant females to stressors, and provide support for the notion that CRF and/or CRF activation of the hypothalamic-pituitary-adrenal axis mediate effects of gestational stress.

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Year:  1995        PMID： 7501659     DOI： 10.1016/0091-3057(95)00082-8

Source DB:  PubMed          Journal:  Pharmacol Biochem Behav        ISSN： 0091-3057            Impact factor:   3.533


  10 in total

1.  Maternal Stressors and Social Support and Risks of Delivering Babies With Gastroschisis or Hypospadias.

Authors:  Suzan L Carmichael; Chen Ma; Sarah Tinker; Gary M Shaw
Journal:  Am J Epidemiol       Date:  2017-06-15       Impact factor: 4.897

2.  Neurobehavioral risk is associated with gestational exposure to stress hormones.

Authors:  Curt A Sandman; Elysia Poggi Davis
Journal:  Expert Rev Endocrinol Metab       Date:  2012-07

3.  Fetal exposure to placental corticotropin-releasing hormone is associated with child self-reported internalizing symptoms.

Authors:  Mariann A Howland; Curt A Sandman; Laura M Glynn; Cheryl Crippen; Elysia Poggi Davis
Journal:  Psychoneuroendocrinology       Date:  2016-02-04       Impact factor: 4.905

4.  Challenges to maternal wellbeing during pregnancy impact temperament, attention, and neuromotor responses in the infant rhesus monkey.

Authors:  Christopher L Coe; Gabriele R Lubach; Heather R Crispen; Elizabeth A Shirtcliff; Mary L Schneider
Journal:  Dev Psychobiol       Date:  2010-11       Impact factor: 3.038

5.  Fetal programming of children's obesity risk.

Authors:  Stephanie A Stout; Emma V Espel; Curt A Sandman; Laura M Glynn; Elysia Poggi Davis
Journal:  Psychoneuroendocrinology       Date:  2014-12-17       Impact factor: 4.905

6.  Prenatal exposure to stressful life events is associated with masculinized anogenital distance (AGD) in female infants.

Authors:  Emily S Barrett; Lauren E Parlett; Sheela Sathyanarayana; Fan Liu; J Bruce Redmon; Christina Wang; Shanna H Swan
Journal:  Physiol Behav       Date:  2013-03-13

7.  Maternal corticosteroid use and hypospadias.

Authors:  Suzan L Carmichael; Chen Ma; Martha M Werler; Richard S Olney; Gary M Shaw
Journal:  J Pediatr       Date:  2009-04-24       Impact factor: 4.406

8.  Transplacental transfer and subsequent neonate utilization of herpes simplex virus-specific immunity are resilient to acute maternal stress.

Authors:  Jodi L Yorty; Robert H Bonneau
Journal:  J Virol       Date:  2003-06       Impact factor: 5.103

9.  Effects of maternal or paternal bisphenol A exposure on offspring behavior.

Authors:  Erin P Harris; Heather A Allardice; A Katrin Schenk; Emilie F Rissman
Journal:  Horm Behav       Date:  2017-10-04       Impact factor: 3.587

10.  Prenatal stress, glucocorticoids and the programming of adult disease.

Authors:  Elizabeth C Cottrell; Jonathan R Seckl
Journal:  Front Behav Neurosci       Date:  2009-09-07       Impact factor: 3.558
  10 in total

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