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Literature DB >> 7497122

Prediction of function in DNA sequence analysis.

Abstract

Recognition of function of newly sequenced DNA fragments is an important area of computational molecular biology. Here we present an extensive review of methods for prediction of functional sites, tRNA, and protein-coding genes and discuss possible further directions of research in this area.

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Year: 1995 PMID： 7497122 DOI： 10.1089/cmb.1995.2.87

Source DB: PubMed Journal: J Comput Biol ISSN： 1066-5277 Impact factor: 1.479

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Cited

18 in total

Review 1. Computational gene finding in plants.

Authors: Mihaela Pertea; Steven L Salzberg
Journal: Plant Mol Biol Date: 2002-01 Impact factor: 4.076

2. Computational analysis of candidate intron regulatory elements for tissue-specific alternative pre-mRNA splicing.

Authors: M Brudno; M S Gelfand; S Spengler; M Zorn; I Dubchak; J G Conboy
Journal: Nucleic Acids Res Date: 2001-06-01 Impact factor: 16.971

3. Prediction of transcription regulatory sites in Archaea by a comparative genomic approach.

Authors: M S Gelfand; E V Koonin; A A Mironov
Journal: Nucleic Acids Res Date: 2000-02-01 Impact factor: 16.971

4. Search for new binding sites for the transcriptional factor SF-1 by the SITECON method: experimental verification and analysis of regulatory regions of orthologous genes.

Authors: E V Ignat'eva; N V Klimova; D Y Oshchepkov; G V Vasil'ev; T I Merkulova; N A Kolchanov
Journal: Dokl Biochem Biophys Date: 2007 Jul-Aug Impact factor: 0.788

Prediction of function in DNA sequence analysis.

Review 1. Computational gene finding in plants.

2. Computational analysis of candidate intron regulatory elements for tissue-specific alternative pre-mRNA splicing.

3. Prediction of transcription regulatory sites in Archaea by a comparative genomic approach.

4. Search for new binding sites for the transcriptional factor SF-1 by the SITECON method: experimental verification and analysis of regulatory regions of orthologous genes.

5. GeneMark.hmm: new solutions for gene finding.

6. Logitlinear models for the prediction of splice sites in plant pre-mRNA sequences.

7. Identification of protein coding regions in the human genome by quadratic discriminant analysis.

8. Analysis of donor splice sites in different eukaryotic organisms.

9. Combining diverse evidence for gene recognition in completely sequenced bacterial genomes.

10. Gene recognition via spliced sequence alignment.