| Literature DB >> 7496976 |
Y L Zou1, M P Van Antwerpen, G Q Shi, Q X Chen, C J Sindic, C Cocito.
Abstract
Tuberculous meningitis cases were analyzed by an immunoblotting test based on Mycobacterium bovis BCG antigen complex A60. Anti-A60 immunoglobulin G (IgG) in cerebrospinal fluid (CSF) allowed early diagnosis, and concentrations decreased after recovery. In primary meningitis forms, anti-A60 IgGs were intrathecally synthesized and specific oligoclonal IgGs were present in CSF. In meningeal complications of pulmonary tuberculosis, there were matching titers of anti-A60 IgG in blood and CSF (mirror pattern). Correlation between CSF-restricted patterns and CSF pleocytosis was shown.Entities:
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Year: 1994 PMID: 7496976 PMCID: PMC368262 DOI: 10.1128/cdli.1.3.353-356.1994
Source DB: PubMed Journal: Clin Diagn Lab Immunol ISSN: 1071-412X