Literature DB >> 7496954

Occurrence, in Crohn's disease, of antibodies directed against a species-specific recombinant polypeptide of Mycobacterium paratuberculosis.

P Vannuffel1, C Dieterich, B Naerhuyzen, P Gilot, M Coene, R Fiasse, C Cocito.   

Abstract

Sera from patients with Crohn's disease and control were analyzed by an enzyme-linked immunosorbent assay based on the Mycobacterium paratuberculosis-specific recombinant polypeptide a362. Anti-a362 immunoglobulin G (IgG) (P < 0.05) and IgA (P < 0.001) titers were higher in patients with Crohn's disease than in controls. A monomodal Gaussian distribution of anti-a362 IgA levels were found for controls, and a bimodal distribution was found for patients with Crohn's disease. An M. paratuberculosis etiology is suggested for the 36% of patients with Crohn's disease who had an anti-a362 IgA level higher than that of controls.

Entities:  

Mesh：

Substances：

Year:  1994        PMID： 7496954      PMCID： PMC368236          DOI： 10.1128/cdli.1.2.241-243.1994

Source DB:  PubMed          Journal:  Clin Diagn Lab Immunol        ISSN： 1071-412X


  20 in total

1.  Immunoglobulin A (IgA) and IgG serum antibodies to mycobacterial antigens in Crohn's disease patients and their relatives.

Authors:  L G Wayne; D Hollander; B Anderson; H A Sramek; C M Vadheim; J I Rotter
Journal:  J Clin Microbiol       Date:  1992-08       Impact factor: 5.948

2.  Mycobacterium paratuberculosis DNA in Crohn's disease tissue.

Authors:  J D Sanderson; M T Moss; M L Tizard; J Hermon-Taylor
Journal:  Gut       Date:  1992-07       Impact factor: 23.059

3.  Use of mixture models in determining laboratory criterion for identification of seropositive individuals: application to parvovirus B19 serology.

Authors:  R A Parker; D D Erdman; L J Anderson
Journal:  J Virol Methods       Date:  1990-02       Impact factor: 2.014

4.  Analysis of human antibody epitopes on the 65-kilodalton protein of Mycobacterium leprae by using synthetic peptides.

Authors:  H C Meeker; D L Williams; D C Anderson; T P Gillis; G Schuller-Levis; W R Levis
Journal:  Infect Immun       Date:  1989-12       Impact factor: 3.441

5.  Cloning and expression of portions of the 34-kilodalton-protein gene of Mycobacterium paratuberculosis: its application to serological analysis of Johne's disease.

Authors:  M De Kesel; P Gilot; M C Misonne; M Coene; C Cocito
Journal:  J Clin Microbiol       Date:  1993-04       Impact factor: 5.948

6.  Composition and immunological properties of the protein fraction of A36, a major antigen complex of Mycobacterium paratuberculosis.

Authors:  M De Kesel; P Gilot; M Coene; C Cocito
Journal:  Scand J Immunol       Date:  1992-08       Impact factor: 3.487

7.  Antibodies to Mycobacterium paratuberculosis-specific protein antigens in Crohn's disease.

Authors:  A Elsaghier; C Prantera; C Moreno; J Ivanyi
Journal:  Clin Exp Immunol       Date:  1992-12       Impact factor: 4.330

8.  Circulating antibodies to heat-shock protein 60 in Crohn's disease and ulcerative colitis.

Authors:  T R Stevens; V R Winrow; D R Blake; D S Rampton
Journal:  Clin Exp Immunol       Date:  1992-11       Impact factor: 4.330

9.  Polymerase chain reaction detection of Mycobacterium paratuberculosis and Mycobacterium avium subsp silvaticum in long term cultures from Crohn's disease and control tissues.

Authors:  M T Moss; J D Sanderson; M L Tizard; J Hermon-Taylor; F A el-Zaatari; D C Markesich; D Y Graham
Journal:  Gut       Date:  1992-09       Impact factor: 23.059

10.  Mycobacterium paratuberculosis and Crohn's disease.

Authors:  K Tanaka; M Wilks; P J Coates; M J Farthing; J A Walker-Smith; S Tabaqchali
Journal:  Gut       Date:  1991-01       Impact factor: 23.059
View more
  6 in total

1.  Familial expression of anti-Saccharomyces cerevisiae mannan antibodies in affected and unaffected relatives of patients with Crohn's disease.

Authors:  C L Sutton; H Yang; Z Li; J I Rotter; S R Targan; J Braun
Journal:  Gut       Date:  2000-01       Impact factor: 23.059

Review 2.  Paratuberculosis.

Authors:  C Cocito; P Gilot; M Coene; M de Kesel; P Poupart; P Vannuffel
Journal:  Clin Microbiol Rev       Date:  1994-07       Impact factor: 26.132

3.  Identification of a novel mycobacterial histone H1 homologue (HupB) as an antigenic target of pANCA monoclonal antibody and serum immunoglobulin A from patients with Crohn's disease.

Authors:  O Cohavy; G Harth; M Horwitz; M Eggena; C Landers; C Sutton; S R Targan; J Braun
Journal:  Infect Immun       Date:  1999-12       Impact factor: 3.441

Review 4.  Current understanding of fungal microflora in inflammatory bowel disease pathogenesis.

Authors:  David Underhill; Jonathan Braun
Journal:  Inflamm Bowel Dis       Date:  2008-08       Impact factor: 5.325

5.  Detection of Mycobacterium avium subsp. paratuberculosis in infected tissues by new species-specific immunohistological procedures.

Authors:  C Coetsier; X Havaux; F Mattelard; S Sadatte; F Cormont; K Buergelt; B Limbourg; D Latinne; H Bazin; J F Denef; C Cocito
Journal:  Clin Diagn Lab Immunol       Date:  1998-07

Review 6.  The zoonotic potential of Mycobacterium avium ssp. paratuberculosis: a systematic review and meta-analyses of the evidence.

Authors:  L A Waddell; A Rajić; K D C Stärk; S A McEWEN
Journal:  Epidemiol Infect       Date:  2015-05-20       Impact factor: 4.434
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.