Literature DB >> 7492372

Antifungal steroidal lactones from Withania coagulance.

M I Choudhary1, Z Parveen, A Jabbar, I Ali.   

Abstract

Two new withanolides, 14,15 beta-epoxywithanolide I [(20S,22R) 17 beta, 20 beta-dihydroxy-14 beta,15 beta-epoxy-1-oxo-witha-3,5,24-trienolide] and 17 beta-hydroxywithanolide K (20S,22R) 14 alpha,17 beta,20 beta-trihydroxy-1-oxo-witha-2,5,24-trienolide] have been isolated from the whole plant of Withania coagulance and their structures were elucidated by spectroscopic techniques. The latter compound was found to be active against a number of potentially pathogenic fungi.

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Year:  1995        PMID： 7492372     DOI： 10.1016/0031-9422(95)00429-b

Source DB:  PubMed          Journal:  Phytochemistry        ISSN： 0031-9422            Impact factor:   4.072


  10 in total

1.  Cytotoxic and other withanolides from aeroponically grown Physalis philadelphica.

Authors:  Ya-Ming Xu; E M Kithsiri Wijeratne; Alan D Brooks; Poonam Tewary; Li-Jiang Xuan; Wen-Qiong Wang; Thomas J Sayers; A A Leslie Gunatilaka
Journal:  Phytochemistry       Date:  2018-05-21       Impact factor: 4.072

2.  Isatinones A and B, new antifungal oxindole alkaloids from Isatis costata.

Authors:  Itrat Fatima; Ijaz Ahmad; Itrat Anis; Abdul Malik; Nighat Afza
Journal:  Molecules       Date:  2007-02-06       Impact factor: 4.411

3.  Isolation of antibacterial compounds from Quercus dilatata L. through bioassay guided fractionation.

Authors:  Maryam Jamil; Ihsan ul Haq; Bushra Mirza; Mazhar Qayyum
Journal:  Ann Clin Microbiol Antimicrob       Date:  2012-05-03       Impact factor: 3.944

4.  Phasic and tonic type A γ-Aminobutryic acid receptor mediated effect of Withania somnifera on mice hippocampal CA1 pyramidal Neurons.

Authors:  Janardhan Prasad Bhattarai; Seong Kyu Han
Journal:  J Ayurveda Integr Med       Date:  2014 Oct-Dec

5.  Antileishmanial, antimicrobial and antifungal activities of some new aryl azomethines.

Authors:  Yasser M S A Al-Kahraman; Hassan M F Madkour; Dildar Ali; Masoom Yasinzai
Journal:  Molecules       Date:  2010-01-28       Impact factor: 4.411

6.  Antimicrobial, antioxidant and cytotoxic properties of Chenopodium glaucum L.

Authors:  Safi Ullah Khan; Faizan Ullah; Sultan Mehmood; Shah Fahad; Arsalan Ahmad Rahi; Fayez Althobaiti; Eldessoky S Dessoky; Shah Saud; Subhan Danish; Rahul Datta
Journal:  PLoS One       Date:  2021-10-29       Impact factor: 3.752

Review 7.  Phytochemistry, Food Application, and Therapeutic Potential of the Medicinal Plant (Withania coagulans): A Review.

Authors:  Muhammad Issa Khan; Maria Maqsood; Raakia Anam Saeed; Amna Alam; Amna Sahar; Marek Kieliszek; Antoni Miecznikowski; Hafiz Shehzad Muzammil; Rana Muhammad Aadil
Journal:  Molecules       Date:  2021-11-15       Impact factor: 4.411

8.  Protective Effect of Withania coagulans Fruit Extract on Cisplatin-induced Nephrotoxicity in Rats.

Authors:  Sonam Sharma; Apurva Joshi; Siva Hemalatha
Journal:  Pharmacognosy Res       Date:  2017 Oct-Dec

9.  Neuroprotective Effect of CR-777, a Glutathione Derivative of Withaferin A, Obtained through the Bioconversion of Withania somnifera (L.) Dunal Extract by the Fungus Beauveria bassiana.

Authors:  Chérif Rabhi; Guillaume Arcile; Géraldine Le Goff; Christian Da Costa Noble; Jamal Ouazzani
Journal:  Molecules       Date:  2019-12-16       Impact factor: 4.411

10.  Molecular characterization of three CYP450 genes reveals their role in withanolides formation and defense in Withania somnifera, the Indian Ginseng.

Authors:  H B Shilpashree; S J Sudharshan; Ajit K Shasany; Dinesh A Nagegowda
Journal:  Sci Rep       Date:  2022-01-31       Impact factor: 4.379
  10 in total

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