Literature DB >> 7491789

Replication of molluscum contagiosum virus.

R M Buller1, J Burnett, W Chen, J Kreider.   

Abstract

Molluscum contagiosum virus (MCV) infects preadolescent children and sexually active adults, frequently causing a disfiguring cutaneous disease in immunosuppressed HIV-infected individuals. The development of an efficacious treatment regime has been hampered by the failure to replicate the virus in the laboratory. Here we report the first demonstration of MCV replication in an experimental system. In human foreskin grafts to athymic mice, MCV induced morphological changes which were indistinguishable from patient biopsies and included the development and migration of molluscum bodies containing mature virions to the epidermal surface.

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Year:  1995        PMID： 7491789     DOI： 10.1006/viro.1995.0037

Source DB:  PubMed          Journal:  Virology        ISSN： 0042-6822            Impact factor:   3.616


  8 in total

1.  Functional characterization of the C---C chemokine-like molecules encoded by molluscum contagiosum virus types 1 and 2.

Authors:  M D Krathwohl; R Hromas; D R Brown; H E Broxmeyer; K H Fife
Journal:  Proc Natl Acad Sci U S A       Date:  1997-09-02       Impact factor: 11.205

2.  Broad spectrum chemokine antagonistic activity of a human poxvirus chemokine homolog.

Authors:  I Damon; P M Murphy; B Moss
Journal:  Proc Natl Acad Sci U S A       Date:  1998-05-26       Impact factor: 11.205

3.  IL-18 binding and inhibition of interferon gamma induction by human poxvirus-encoded proteins.

Authors:  Y Xiang; B Moss
Journal:  Proc Natl Acad Sci U S A       Date:  1999-09-28       Impact factor: 11.205

4.  Correspondence of the functional epitopes of poxvirus and human interleukin-18-binding proteins.

Authors:  Y Xiang; B Moss
Journal:  J Virol       Date:  2001-10       Impact factor: 5.103

5.  Molluscum Contagiosum Virus Transcriptome in Abortively Infected Cultured Cells and a Human Skin Lesion.

Authors:  Jorge D Mendez-Rios; Zhilong Yang; Karl J Erlandson; Jeffrey I Cohen; Craig A Martens; Daniel P Bruno; Stephen F Porcella; Bernard Moss
Journal:  J Virol       Date:  2016-04-14       Impact factor: 5.103

6.  Identification from diverse mammalian poxviruses of host-range regulatory genes functioning equivalently to vaccinia virus C7L.

Authors:  Xiangzhi Meng; Jie Chao; Yan Xiang
Journal:  Virology       Date:  2007-12-03       Impact factor: 3.616

7.  Molluscum contagiosum virus expresses late genes in primary human fibroblasts but does not produce infectious progeny.

Authors:  J J Bugert; N Melquiot; R Kehm
Journal:  Virus Genes       Date:  2001-01       Impact factor: 2.198

8.  Seroprevalence of Molluscum contagiosum virus in German and UK populations.

Authors:  Subuhi Sherwani; Laura Farleigh; Nidhi Agarwal; Samantha Loveless; Neil Robertson; Eva Hadaschik; Paul Schnitzler; Joachim Jakob Bugert
Journal:  PLoS One       Date:  2014-02-18       Impact factor: 3.240
  8 in total

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