S Holmäng1, G Borghede. 1. Department of Urology, Sahlgrenska University Hospital, Göteborg, Sweden.
Abstract
PURPOSE: We studied the early side effects and survival rates after short-term radiotherapy (7 Gy. 3 times or 5 Gy. 4 times) in patients with muscle invasive bladder carcinoma. MATERIALS AND METHODS: Between 1981 and 1992, 96 patients (median age 80 years) were treated. Followup was complete until 1994 or death. RESULTS: Early side effects caused the hospitalization of 22 patients and may have contributed to the death of 5 elderly patients. Median survival for patients with stages T2M0, T3M0, T4M0 and T2 to 4M+ disease was 27 months, 6.3 months, 5.6 months and 2.9 months, respectively. CONCLUSIONS: Short-term radiotherapy is of doubtful benefit to elderly patients with advanced bladder carcinoma and may even be harmful.
PURPOSE: We studied the early side effects and survival rates after short-term radiotherapy (7 Gy. 3 times or 5 Gy. 4 times) in patients with muscle invasive bladder carcinoma. MATERIALS AND METHODS: Between 1981 and 1992, 96 patients (median age 80 years) were treated. Followup was complete until 1994 or death. RESULTS: Early side effects caused the hospitalization of 22 patients and may have contributed to the death of 5 elderly patients. Median survival for patients with stages T2M0, T3M0, T4M0 and T2 to 4M+ disease was 27 months, 6.3 months, 5.6 months and 2.9 months, respectively. CONCLUSIONS: Short-term radiotherapy is of doubtful benefit to elderly patients with advanced bladder carcinoma and may even be harmful.
Authors: C De Nunzio; A Cicione; F Leonardo; M Rondoni; G Franco; A Cantiani; A Tubaro; C Leonardo Journal: Int Urol Nephrol Date: 2010-11-26 Impact factor: 2.370
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