Literature DB >> 7489438

Intrathecal morphine (ITM) for postoperative pain control in children: a comparison with nalbuphine patient controlled analgesia (PCA).

S W Krechel1, M A Helikson, D Kittle, G W Eggers.   

Abstract

This is a retrospective study covering the ten-year period 1984-1993. Single shot spinal morphine (ITM) is compared with PCA nalbuphine for postoperative pain relief in children having abdominal or thoracic procedures. The records of 52 patients meeting selection criteria were examined. Nursing and physician notations were reviewed for hourly pain assessments, evidence of associated complications, respiratory depression, nausea and or vomiting, pruritus, and urinary retention. ITM provided significantly better pain relief (2.2 h in pain) during the first 24 h postoperatively than PCA nalbuphine (9.2 h in pain). With the exception of urinary retention which was significantly more frequent following ITM (58.6%) compared to PCA nalbuphine (8.7%), narcotic related complications were not different between the two groups. No difference in duration of hospital stay or ICU stay could be demonstrated. We conclude that ITM provides better pain relief, without more serious complications, than PCA nalbuphine. We recommend it as a safe, effective technique to treat postoperative pain in children following thoracic or upper abdominal procedures.

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Year:  1995        PMID: 7489438     DOI: 10.1111/j.1460-9592.1995.tb00274.x

Source DB:  PubMed          Journal:  Paediatr Anaesth        ISSN: 1155-5645            Impact factor:   2.556


  2 in total

1.  Validation of a preclinical spinal safety model: effects of intrathecal morphine in the neonatal rat.

Authors:  B David Westin; Suellen M Walker; Ronald Deumens; Marjorie Grafe; Tony L Yaksh
Journal:  Anesthesiology       Date:  2010-07       Impact factor: 7.892

2.  [Intrathecal opioid medication for perioperative analgesia in severely handicapped children undergoing spinal operations].

Authors:  A Schmitz; B Salgo; M Weiss; C M Dillier; A Frotzler; A C Gerber
Journal:  Anaesthesist       Date:  2010-07       Impact factor: 1.041

  2 in total

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