| Literature DB >> 7488027 |
J A Visser1, A McLuskey, T van Beers, D O Weghuis, A G van Kessel, J A Grootegoed, A P Themmen.
Abstract
Using the rat anti-müllerian hormone type II receptor (AMHRII) cDNA as a probe, two overlapping lambda phage clones containing the AMHRII gene were isolated from a human genomic library. Sequence analysis of the exons was performed and the exon/intron boundaries were determined. The coding region was found to consist of 11 exons, divided over 8 kb. The genomic structure resembles that of the related activin type II receptor gene. The AMHRII gene was mapped to human chromosome 12q12-q13. The results reported are essential for identification of AMHRII gene alterations in patients with persistent müllerian duct syndrome.Entities:
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Year: 1995 PMID： 7488027 DOI： 10.1006/bbrc.1995.2567
Source DB: PubMed Journal: Biochem Biophys Res Commun ISSN： 0006-291X Impact factor: 3.575