| Literature DB >> 7483290 |
Abstract
Comparison of the genomic organization of variola and vaccinia viruses has been carried out. Molecular factors of virulence of these viruses is the focus of this review. Possible roles of the genes of soluble cytokine receptors, complement control proteins, factors of virus replication, and dissemination in vivo for variola virus pathogenesis are discussed. The existence of "buffer" genes in the vaccinia virus genome is proposed.Entities:
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Year: 1995 PMID: 7483290 DOI: 10.1007/bf01724297
Source DB: PubMed Journal: Virus Genes ISSN: 0920-8569 Impact factor: 2.332