Literature DB >> 7480130

The role of urocanic acid in UV-induced immunosuppression: recent advances (1992-1994).

M Norval1, N K Gibbs, J Gilmour.   

Abstract

Cis-urocanic acid (UCA), formed in the epidermis by UV irradiation of trans-UCA, has been implicated as a mediator of the immunosuppression induced by UV exposure of the skin. This review covers recent work in which the wavelength dependence of cis-UCA formation, the interaction of UCA isomers with DNA, the effects of UCA isomers on the immune system and their interaction with histamine are examined. Results are frequently conflicting, particularly when considering the possible mode of action of cis-UCA but, overall, a multifaceted role for UCA in immunomodulation by UV radiation is substantiated.

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Year:  1995        PMID： 7480130     DOI： 10.1111/j.1751-1097.1995.tb05261.x

Source DB:  PubMed          Journal:  Photochem Photobiol        ISSN： 0031-8655            Impact factor:   3.421


  9 in total

Review 1.  Prevention of Photocarcinogenesis by Agonists of 5-HT1A and Antagonists of 5-HT2A Receptors.

Authors:  Ana Catarina Menezes; Sara Raposo; Sandra Simões; Helena Ribeiro; Helena Oliveira; Andreia Ascenso
Journal:  Mol Neurobiol       Date:  2015-01-15       Impact factor: 5.590

2.  Urocanic acid as an efficient hydroxyl radical scavenger: a quantum theoretical study.

Authors:  Saumya Tiwari; Phool Chand Mishra
Journal:  J Mol Model       Date:  2010-04-02       Impact factor: 1.810

3.  Histamine involvement in UVB- and cis-urocanic acid-induced systemic suppression of contact hypersensitivity responses.

Authors:  P H Hart; A Jaksic; G Swift; M Norval; A A el-Ghorr; J J Finlay-Jones
Journal:  Immunology       Date:  1997-08       Impact factor: 7.397

4.  Heme oxygenase induction mediates the photoimmunoprotective activity of UVA radiation in the mouse.

Authors:  V E Reeve; R M Tyrrell
Journal:  Proc Natl Acad Sci U S A       Date:  1999-08-03       Impact factor: 11.205

5.  The role of urocanic acid in UVB-induced suppression of immunity to Trichinella spiralis infection in the rat.

Authors:  J Garssen; M Norval; J Crosby; P Dortant; H Van Loveren
Journal:  Immunology       Date:  1999-02       Impact factor: 7.397

6.  Cis-urocanic acid, a sunlight-induced immunosuppressive factor, activates immune suppression via the 5-HT2A receptor.

Authors:  Jeffrey P Walterscheid; Dat X Nghiem; Nasser Kazimi; Leta K Nutt; David J McConkey; Mary Norval; Stephen E Ullrich
Journal:  Proc Natl Acad Sci U S A       Date:  2006-11-03       Impact factor: 11.205

Review 7.  Sunlight and skin cancer: lessons from the immune system.

Authors:  Stephen E Ullrich
Journal:  Mol Carcinog       Date:  2007-08       Impact factor: 4.784

Review 8.  Photoimmunology--illuminating the immune system through photobiology.

Authors:  Justin Leitenberger; Heidi T Jacobe; Ponciano D Cruz
Journal:  Semin Immunopathol       Date:  2007-04       Impact factor: 11.759

Review 9.  Effects of narrow band UVB (311 nm) irradiation on epidermal cells.

Authors:  Adam Reich; Karolina Mędrek
Journal:  Int J Mol Sci       Date:  2013-04-17       Impact factor: 5.923
  9 in total

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