| Literature DB >> 7479040 |
R Wagner1, P Debbie, M Radman.
Abstract
An accurate and highly sensitive mutation detection assay has been developed. The assay is based on the detection of mispaired and unpaired bases by immobilized mismatch binding protein (Escherichia coli MutS). The assay can detect most mismatches and all single base substitution mutations, as well as small addition or deletion mutations. The assay is simple to use and does not require the use of either radioactivity or gel electrophoresis.Entities:
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Year: 1995 PMID: 7479040 PMCID: PMC307314 DOI: 10.1093/nar/23.19.3944
Source DB: PubMed Journal: Nucleic Acids Res ISSN: 0305-1048 Impact factor: 16.971