Literature DB >> 747713

Effect of antibody avidity on the induction of renal injury in anti-glomerular basement membrane nephritis.

F Shimizu, H Mossmann, H Takamiya, A Vogt.   

Abstract

Antibodies to glomerular basement membrane (GBM) of the rat could be fractionated according to their avidity by elution from trypsin-digested GBM (bound to Sepharose) with increasing concentrations of KSCN. The percentage of kidney-fixing antibody in each fraction and the degree of proteinuria induced as determined 24 h after injection increased with the avidity of the antibody fraction when equal doses were administered.

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Year:  1978        PMID： 747713      PMCID： PMC2041398     

Source DB:  PubMed          Journal:  Br J Exp Pathol        ISSN： 0007-1021


  13 in total

1.  Localization of the nephrotoxic antigen within the isolated renal glomerulus.

Authors:  C A KRAKOWER; S A GREENSPON
Journal:  AMA Arch Pathol       Date:  1951-06

2.  Differences in the isoelectric focussing pattern of antibodies to human serum albumin eluted from an immunoadsorbent (HSA-sepharose) with thiocyanate ions.

Authors:  F Shimizu; M Kist; A Vogt
Journal:  Res Exp Med (Berl)       Date:  1978-06-12

3.  A method of trace iodination of proteins for immunologic studies.

Authors:  P J McConahey; F J Dixon
Journal:  Int Arch Allergy Appl Immunol       Date:  1966

4.  A glycoprotein that induces nephrotoxic antibody: its isolation and purification from rat glomerular basement membrane.

Authors:  S Shibata; Y Miyakawa; T Naruse; T Nagasawa; T Takuma
Journal:  J Immunol       Date:  1969-03       Impact factor: 5.422

5.  Effect of variation in antibody-hapten association constant upon the biologic activity of the antibody.

Authors:  G W Siskind; H N Eisen
Journal:  J Immunol       Date:  1965-09       Impact factor: 5.422

6.  The immunopathological significance of the heterogeneity of antibody affinity.

Authors:  J F Soothill; M W Steward
Journal:  Clin Exp Immunol       Date:  1971-08       Impact factor: 4.330

7.  Separation of anti-dinitrophenyl antibodies according to affinity by fractionated elution from immunoadsorbent using thiocyanate.

Authors:  F Shimizu; H Mossmann; K Himmelspach; H Takamiya; A Vogt
Journal:  Res Exp Med (Berl)       Date:  1978-08-15

8.  The role of low affinity antibody in immune complex disease. The quantity of anti-DNA antibodies in NZB/W F1 hybrid mice.

Authors:  M W Steward; F E Katz; N J West
Journal:  Clin Exp Immunol       Date:  1975-07       Impact factor: 4.330

9.  The glomerular mesangium. I. Kinetic studies of macromolecular uptake in normal and nephrotic rats.

Authors:  S M Mauer; A J Fish; E B Blau; A F Michael
Journal:  J Clin Invest       Date:  1972-05       Impact factor: 14.808

10.  EXPERIMENTAL GLOMERULONEPHRITIS. V. STUDIES ON THE INTERACTION OF NEPHROTOXIC ANTIBODIES WITH TISSUE OF THE RAT.

Authors:  E R UNANUE; F J DIXON
Journal:  J Exp Med       Date:  1965-05-01       Impact factor: 14.307
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  2 in total

1.  The Goodpasture-like syndrome in mice induced by intravenous injections of anti-type IV collagen and anti-laminin antibody.

Authors:  M Yaar; J M Foidart; K S Brown; S I Rennard; G R Martin; L Liotta
Journal:  Am J Pathol       Date:  1982-04       Impact factor: 4.307

2.  High affinity antibodies to Plasmodium falciparum merozoite antigens are associated with protection from malaria.

Authors:  Sreenivasulu B Reddy; Robin F Anders; James G Beeson; Anna Färnert; Fred Kironde; Sharon Kühlman Berenzon; Mats Wahlgren; Sara Linse; Kristina E M Persson
Journal:  PLoS One       Date:  2012-02-21       Impact factor: 3.240
  2 in total

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