Literature DB >> 7474640

[Tuberculous spondylitis after intravesical BCG instillation: a case report].

Y Sugita1, H Chokyu, A Gotoh, H Maeda, K Umezu, Y Nakano.   

Abstract

We report a case of tuberculous spondylitis after intravesical bacillus Calmette-Guerin (BCG) instillation. A 71-year-old man was administered BCG (80 mg per week) for 8 weeks for prophylactic treatment of bladder cancer. After the first instillation he experienced miction pain, pollakisuria, and febrile episodes. Two months after the completion of BCG instillation, he complained to back pain and spinal X-ray showed a lytic lesion of Th7 vertebra. Diagnosis of metastatic transitional cell carcinoma was made based on MRI and bone scan. But pathological findings at laminectomy revealed tuberculous spondylitis. Antituberculous therapy (SM, RFP, and INH) was instituted and anterior supine fusion was performed. Now he is free from bladder cancer and tuberculous infection. Intravesical BCG instillation is effective for superficial bladder cancer, but it should be kept in mind that complications related to this treatment could occur and the adequate antituberculosis treatment has to be insisted if indicated.

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Year:  1995        PMID: 7474640     DOI: 10.5980/jpnjurol1989.86.1493

Source DB:  PubMed          Journal:  Nihon Hinyokika Gakkai Zasshi        ISSN: 0021-5287


  3 in total

1.  A case of Pott's disease with epidural abscess and probable cerebral tuberculoma following Bacillus Calmette-Guérin therapy for superficial bladder cancer.

Authors:  Colin B Josephson; Saleh Al-Azri; Daniel J Smyth; David Haase; B Lynn Johnston
Journal:  Can J Infect Dis Med Microbiol       Date:  2010       Impact factor: 2.471

2.  Mycobacterium bovis spondylodiscitis after intravesical Bacillus Calmette-Guérin therapy.

Authors:  Sami Obaid; Alexander G Weil; Ralph Rahme; Cathy Gendron; Daniel Shedid
Journal:  Surg Neurol Int       Date:  2011-11-14

Review 3.  Bacille Calmette-Guérin (BCG) spondylitis with adjacent mycotic aortic aneurysm after intravesical BCG therapy: a case report and literature review.

Authors:  Takuya Kusakabe; Kenji Endo; Itaru Nakamura; Hidekazu Suzuki; Hirosuke Nishimura; Shinji Fukushima; Kengo Yamamoto
Journal:  BMC Infect Dis       Date:  2018-06-28       Impact factor: 3.090

  3 in total

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