Literature DB >> 7472598

Metabolic mismatch of septal beta-oxidation and glucose utilization in left bundle branch block assessed with PET.

C Altehoefer1, J vom Dahl, R Bares, G L Stöcklin, U Büll.   

Abstract

Preserved septal uptake of the new long-chain fatty acid analog [18F]FTHA was found in a patient with three-vessel disease, a history of previous anterior myocardial infarction and left bundle branch block (LBBB), despite severely decreased septal [18F]FDG uptake that suggested scarred tissue. Nearly absent [19F]FDG uptake in the septum could not be explained by concordant reduction of septal perfusion as assessed by 99mTc-MIBI SPECT. These data may point to divergent metabolic effects of the conduction abnormality in LBBB with consecutively reduced septal exogenous glucose utilization but unaffected septal beta-oxidation.

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Year:  1995        PMID: 7472598

Source DB:  PubMed          Journal:  J Nucl Med        ISSN: 0161-5505            Impact factor:   10.057


  5 in total

1.  Altered myocardial glucose utilization and the reverse mismatch pattern on rubidium-82 perfusion/F-18-FDG PET during the sub-acute phase following reperfusion of acute anterior myocardial infarction.

Authors:  Daniel D Anselm; Anjali H Anselm; Jennifer Renaud; Harold L Atkins; Robert de Kemp; Ian G Burwash; Kathryn A Williams; Ann Guo; Cathy Kelly; Jean Dasilva; Rob S B Beanlands; Christopher A Glover
Journal:  J Nucl Cardiol       Date:  2011-05-13       Impact factor: 5.952

2.  Assessment of myocardial fatty acid metabolism in atrioventricular synchronous pacing: analysis of iodine 123-labeled beta-methyl iodophenyl pentadecanoic acid SPECT.

Authors:  H Yoshida; M Shirotani; M Mochizuki; K Sakata
Journal:  J Nucl Cardiol       Date:  1999 Jan-Feb       Impact factor: 5.952

Review 3.  Metabolic imaging using PET.

Authors:  Takashi Kudo
Journal:  Eur J Nucl Med Mol Imaging       Date:  2007-05-05       Impact factor: 9.236

Review 4.  Animal models of dyssynchrony.

Authors:  Marc Strik; Lars B van Middendorp; Kevin Vernooy
Journal:  J Cardiovasc Transl Res       Date:  2011-12-01       Impact factor: 4.132

5.  Septal and anterior reverse mismatch of myocardial perfusion and metabolism in patients with coronary artery disease and left bundle branch block.

Authors:  Jian-Guang Wang; Wei Fang; Min-Fu Yang; Yue-Qin Tian; Xiao-Li Zhang; Rui Shen; Xiao-Xin Sun; Feng Guo; Dao-Yu Wang; Zuo-Xiang He
Journal:  Medicine (Baltimore)       Date:  2015-05       Impact factor: 1.889

  5 in total

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