Literature DB >> 7470841

Reaction time in Parkinson's disease.

E V Evarts, H Teräväinen, D B Calne.   

Abstract

Both reaction time and movement time tend to be prolonged in Parkinson's disease, but they are often impaired independently of each other. Prolongation of RT is relatively slight, while MT undergoes more substantial and consistent disturbance. Choice RT and kinaesthetic RT do not have any advantage over simple visual RT as measurements of neurological deficit in parkinsonism, since they are all impaired to the same extent. MT is more useful than RT as an objective indicator of therapeutic efficacy, but further studies of RT (with tests requiring programming of displacement, velocity, and accuracy) may provide insights into the nature of the central motor disorder in Parkinson's disease.

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Year:  1981        PMID: 7470841     DOI: 10.1093/brain/104.1.167

Source DB:  PubMed          Journal:  Brain        ISSN: 0006-8950            Impact factor:   13.501


  73 in total

1.  Metabotropic glutamate 5 receptor blockade alleviates akinesia by normalizing activity of selective basal-ganglia structures in parkinsonian rats.

Authors:  Nathalie Breysse; Marianne Amalric; Pascal Salin
Journal:  J Neurosci       Date:  2003-09-10       Impact factor: 6.167

2.  Cognitive components of reaction time in Parkinson's disease.

Authors:  N Jordan; H J Sagar; J A Cooper
Journal:  J Neurol Neurosurg Psychiatry       Date:  1992-08       Impact factor: 10.154

3.  Practice effects on the preprogramming of discrete movements in Parkinson's disease.

Authors:  C J Worringham; G E Stelmach
Journal:  J Neurol Neurosurg Psychiatry       Date:  1990-08       Impact factor: 10.154

Review 4.  Motor control abnormalities in Parkinson's disease.

Authors:  Pietro Mazzoni; Britne Shabbott; Juan Camilo Cortés
Journal:  Cold Spring Harb Perspect Med       Date:  2012-06       Impact factor: 6.915

5.  Proprioceptive reaction times and long-latency reflexes in humans.

Authors:  C D Manning; S A Tolhurst; P Bawa
Journal:  Exp Brain Res       Date:  2012-07-06       Impact factor: 1.972

Review 6.  Sharpening the boundaries of Parkinson-associated dementia: recommendation for a neuropsychological diagnostic procedure.

Authors:  Marc R Bothe; Ingo Uttner; Markus Otto
Journal:  J Neural Transm (Vienna)       Date:  2010-01-30       Impact factor: 3.575

7.  Amantadine sulphate in treating Parkinson's disease: clinical effects, psychometric tests and serum concentrations.

Authors:  M Brenner; A Haass; P Jacobi; K Schimrigk
Journal:  J Neurol       Date:  1989-03       Impact factor: 4.849

8.  Motor switching abilities in Parkinson's disease and old age: temporal aspects.

Authors:  M Plotnik; T Flash; R Inzelberg; E Schechtman; A D Korczyn
Journal:  J Neurol Neurosurg Psychiatry       Date:  1998-09       Impact factor: 10.154

9.  Robot-Aided Neurorehabilitation: A Pediatric Robot for Ankle Rehabilitation.

Authors:  Konstantinos P Michmizos; Stefano Rossi; Enrico Castelli; Paolo Cappa; Hermano Igo Krebs
Journal:  IEEE Trans Neural Syst Rehabil Eng       Date:  2015-03-06       Impact factor: 3.802

10.  Event-related desynchronization/synchronization during discrimination task conditions in patients with Parkinson's disease.

Authors:  Juliana Dushanova; Dolja Philipova; Gloria Nikolova
Journal:  Cell Mol Neurobiol       Date:  2009-03-17       Impact factor: 5.046

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