Literature DB >> 7469901

Inhibition of experimental esophageal lye strictures by penicillamine.

P Gehanno, C Guedon.   

Abstract

We describe a new experimental model for the study of caustic stenosis of the esophagus in the rat. Sixty-five Wistar rats were given a standard esophageal lye burn. Animals were divided into two groups: (1) a control group and (2) a treatment group that received penicillamine from the day after the esophageal lye burn. Stenosis developed in only two of the 23 treated rats. Our conclusion is that penicillamine-induced lathyrism inhibits the onset of stenosis in the rat. Double-blind controlled studies of the effect of penicillamine in the prevention of corrosive strictures of the esophagus in man seem warranted.

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Year:  1981        PMID： 7469901     DOI： 10.1001/archotol.1981.00790390011004

Source DB:  PubMed          Journal:  Arch Otolaryngol        ISSN： 0003-9977


  25 in total

1.  A novel approach for preventing esophageal stricture formation: sphingosylphosphorylcholine-enhanced tissue remodeling.

Authors:  Aydin Yagmurlu; Burhan Aksu; Meltem Bingol-Kologlu; Nurten Renda; Gulcin Altinok; Suat Fitoz; I Haluk Gokcora; Huseyin Dindar
Journal:  Pediatr Surg Int       Date:  2004-10       Impact factor: 1.827

2.  Effect of the prostacyclin derivate iloprost in experimental caustic esophageal burn.

Authors:  G Ekingen; M Ozden; S Sözübir; H Maral; B Müezzinoğlu; H Kahraman; B H Güvenç
Journal:  Pediatr Surg Int       Date:  2005-04-28       Impact factor: 1.827

3.  The route of the catheter directly affects the volume needed in experimental corrosive esophagitis.

Authors:  Vahit Yukselen; Nevin Oruc; Omer Ozutemiz
Journal:  Pediatr Surg Int       Date:  2008-09-23       Impact factor: 1.827

Review 4.  Caustic injury of the oesophagus.

Authors:  Alastair J W Millar; Sharon G Cox
Journal:  Pediatr Surg Int       Date:  2014-11-29       Impact factor: 1.827

5.  Management of severe caustic stenosis of the hypopharynx and esophagus by ileocolic transposition via suprahyoid or transepiglottic approach. Analysis of 18 cases.

Authors:  P Tran Ba Huy; M Celerier
Journal:  Ann Surg       Date:  1988-04       Impact factor: 12.969

6.  Protective effects of ibuprofen against caustic esophageal burn injury in rats.

Authors:  Ozkan Herek; Murat Karabul; Ciğdem Yenisey; Muhan Erkuş
Journal:  Pediatr Surg Int       Date:  2010-05-18       Impact factor: 1.827

7.  New experimental corrosive esophagitis model in rats.

Authors:  Ekrem Senturk; Serdar Sen; Engin Pabuccu; Cengiz Unsal; Ibrahim Meteoglu
Journal:  Pediatr Surg Int       Date:  2009-12-11       Impact factor: 1.827

8.  Resveratrol attenuates inflammation and stricture formation in experimental caustic esophageal burns.

Authors:  S Uguralp; C Irsi; T Aksoy; A Bay Karabulut; H Kirimlioglu; B Mizrak
Journal:  Pediatr Surg Int       Date:  2008-02-19       Impact factor: 1.827

9.  Ketotifen ameliorates development of fibrosis in alkali burns of the esophagus.

Authors:  Vahit Yukselen; Ali Onder Karaoglu; Omer Ozutemiz; Cigdem Yenisey; Muge Tuncyurek
Journal:  Pediatr Surg Int       Date:  2004-04-24       Impact factor: 1.827

10.  Biochemical and histopathologic effects of omeprazole and vitamin E in rats with corrosive esophageal burns.

Authors:  Banu Topaloglu; Unal Bicakci; Burak Tander; Ender Ariturk; Birsen Kilicoglu-Aydin; Oguz Aydin; Riza Rizalar; Suat H Ayyildiz; Ferit Bernay
Journal:  Pediatr Surg Int       Date:  2008-03-20       Impact factor: 1.827
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